Repeated exposures to roadside particulate matter extracts suppresses pulmonary defense mechanisms, resulting in lipid and protein oxidative damage

M Pardo, Z Porat, A Rudich, JJ Schauer… - Environmental Pollution, 2016 - Elsevier
Exposure to particulate matter (PM) pollution in cities and urban canyons can be harmful to
the exposed population. However, the underlying mechanisms that lead to health effects are …

[HTML][HTML] The combined effects of physicochemical properties of size-fractionated ambient particulate matter on in vitro toxicity in human A549 lung epithelial cells

US Akhtar, N Rastogi, RD McWhinney, B Urch… - Toxicology Reports, 2014 - Elsevier
Epidemiological and toxicological studies have suggested that the health effects associated
with exposure to particulate matter (PM) are related to the different physicochemical …

Prooxidant and Proinflammatory Potency of Air Pollution Particulate Matter (PM2.5–0.3) Produced in Rural, Urban, or Industrial Surroundings in Human Bronchial …

M Dergham, C Lepers, A Verdin, S Billet… - Chemical research in …, 2012 - ACS Publications
Compelling evidence indicates that exposure to air pollution particulate matter (PM) affects
human health. However, how PM composition interacts with PM-size to cause adverse …

Spatial and seasonal heterogeneity of atmospheric particles induced reactive oxygen species in urban areas and the role of water-soluble metals

NK Gali, F Yang, SY Jiang, KL Chan, L Sun, K Ho… - Environmental …, 2015 - Elsevier
Adverse health effects are associated with exposure to atmospheric particulate matter (PM),
which carry various chemical constituents and induce both exogenous and endogenous …

Decreased CD11b expression, phagocytosis, and oxidative burst in urban particulate pollution-exposed human monocytes and alveolar macrophages

S Becker - Journal of Toxicology and Environmental Health Part A, 1998 - Taylor & Francis
Elevated levels of air pollution particulates 10 mum in diameter (PM10) have been
associated with an increase in mortality and morbidity due to pulmonary complications …

Lung antioxidant depletion: a predictive indicator of cellular stress induced by ambient fine particles

B Crobeddu, I Baudrimont, J Deweirdt… - Environmental …, 2020 - ACS Publications
Regulations on ambient particulate matter (PM) are becoming more stringent because of
adverse health effects arising from PM exposure. PM-induced oxidant production is a key …

Acetaldehyde (CH3CHO) production in rodent lung after exposure to metal-rich particles

MC Madden, MJ Thomas, AJ Ghio - Free Radical Biology and Medicine, 1999 - Elsevier
Epidemiological reports demonstrate an association between increased human morbidity
and mortality with exposure to air pollution particulate matter (PM). Metal-catalyzed oxidative …

Review of acellular assays of ambient particulate matter oxidative potential: methods and relationships with composition, sources, and health effects

JT Bates, T Fang, V Verma, L Zeng… - … science & technology, 2019 - ACS Publications
Oxidative stress is a potential mechanism of action for particulate matter (PM) toxicity and
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …

Oxidative stress and air pollution exposure

M Lodovici, E Bigagli - Journal of toxicology, 2011 - Wiley Online Library
Air pollution is associated with increased cardiovascular and pulmonary morbidity and
mortality. The mechanisms of air pollution‐induced health effects involve oxidative stress …

Relationship between redox activity and chemical speciation of size-fractionated particulate matter

L Ntziachristos, JR Froines, AK Cho… - Particle and fibre toxicology, 2007 - Springer
Background Although the mechanisms of airborne particulate matter (PM) related health
effects remain incompletely understood, one emerging hypothesis is that these adverse …