The epidermis is the outermost layer of mammalian skin and comprises a multilayered
epithelium, the interfollicular epidermis, with associated hair follicles, sebaceous glands …

Although the existence of epithelial stem cells in the skin has been known for some decades
from cell kinetic studies performed in vivo, attempts to prospectively isolate these cells for …

Epidermal stem cells play a central role in tissue homeostasis, wound repair, tumor initiation,
and gene therapy. A major impediment to the purification and molecular characterization of …

This is a chronicle of concepts in the field of epidermal stem cell biology and a historic look
at their development over time. The past 25 years have seen the evolution of epidermal stem …

The clinical implications of understanding epidermal stem cell biology abound. Thousands
of burns victims across the world have benefited from early research into the proliferation of …

The field of epidermal stem cells has dramatically advanced in the last decade, leading to a
better understanding of the molecular factors, signalling pathways and cellular events that …

Throughout adult life, the epidermis and the hair follicle undergo a perpetual cycle of growth,
regression and rest. Stem cells in the epidermis not only ensure the maintenance of …

BACKGROUND: The epidermis is an important protective barrier that is essential for
maintenance of life. Maintaining this barrier requires continuous cell proliferation and …

Lineage tracing involves labeling cells to track their subsequent behavior within the normal
tissue environment. The advent of genetic lineage tracing and cell proliferation assays …

The skin constantly renews itself throughout adult life, and the hair follicle undergoes a
perpetual cycle of growth and degeneration. Stem cells (SCs) residing in the epidermis and …