Increasing evidence indicates that excessive iron in selective regions of the brain may be
involved in the etiology of neurodegenerative disorders. Accordingly, increased levels of …

Iron accumulation in the brain has been implicated in the pathogenesis of
neurodegenerative disorders. It is known that iron catalyses the formation of highly reactive …

Excess of iron in the brain has been implicated in the pathogenesis of several human
neurodegenerative diseases, for example Alzheimer's disease and Parkinson's disease. It …

Over the last decades, studies from our laboratory and other groups using animal models
have shown that iron overload, resulting in iron accumulation in the brain, produces …

Excess iron in the brain has been implicated in the pathogenesis of several human
neurodegenerative disorders, ie, Parkinson's and Alzheimer's disease. The neonatal period …

Iron is essential for normal neurological function because of its role in oxidative metabolism
and because it is a cofactor in the synthesis of neurotransmitters and myelin. In the past …

In this study, we investigated the cellular distribution of iron in the brain of Belgrade rats.
These rats have a mutation in Divalent Metal Transporter 1, which has been implicated in …

Oxidative stress, cellular damage, and neuronal apoptosis are believed to underlie the
progressive cognitive decline that accompanies natural aging and to be exacerbated in …

Iron accumulation in the brain has been associated to the pathogenesis of
neurodegenerative disorders. We have previously demonstrated that iron overload in the …

Increased levels of iron in brain regions have been reported in neurodegenerative disorders
as well as in normal brain aging. We have previously demonstrated that neonatal iron …