Pyrazolines are preferred to be stable heterocycles in medication development. It has been
established from previous research that the 2‐pyrazolone scaffold is a common pattern that …

Pyrazolines are five-membered heterocyclic compounds containing two nitrogen atoms that
represent a privileged scaffold for various bioactive compounds with diverse …

Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …

Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

Background: Anxiety and oxidative stress are the common disorders prevailing in the
modern age. Many new pyrazoline derivatives have been synthesized and patented, but …

Introduction: Pyrazolines are well-known and important nitrogen-containing five-membered
ring heterocyclic compounds. Various methods have been worked out for their synthesis …

Abstract A novel series of 1, 3, 5-trisubstituted-2-pyrazoline derivatives (PFC-1 to PFC-16)
were synthesized in a three step reaction using conventional and microwave assisted green …

Abstract A novel series of 1, 3, 5-trisubstituted-2-pyrazolines (5a-5t) was prepared via
Claisen Schmidt condensation, followed by heterocyclization with hydrazine hydrate …

Objective: This study is undertaken to design and synthesize new pyrazoline derivatives and
to evaluate their antidepressant efficacy by in silico and in vivo studies. Materials and …

The prevalence of cancer and neurodegenerative diseases, such as Alzheimer's and
Parkinson's, continues to rise worldwide, presenting a significant health burden. Despite …