This study addresses the transport mechanism of riboflavin (vitamin B2) across intestinal
epithelium in the presence and absence of pharmacologically active compounds. A …

Previous studies by our laboratory have suggested the potential role of receptor-mediated
endocytosis components in the cellular translocation of riboflavin (vitamin B2). To delineate …

The role of riboflavin in cell maintenance and growth, and the mechanism by which it is
absorbed into various human tissues and cell lines has been extensively studied over the …

Carriers involved in riboflavin transport have generally been presumed to be localized in the
upper small intestine. However, using a closed loop technique, we found that in the rat colon …

The present study was aimed at kinetically characterizing the newly found carrier-mediated
riboflavin transport system in the rat colon, comparing it with that in the small intestine, and …

Riboflavin, also known as vitamin B2, is transported across the biological membrane into
various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small …

Background Uptake of riboflavin (RF) by intestinal epithelial cells occurs via a specific carrier-
mediated process that involves the apically localized RF transporter-3 (RFVT3). Previous …

The cellular and molecular regulation of intestinal absorption of the water-soluble vitamin
riboflavine (RF) is poorly understood. The availability of a suitable in vitro cultured system …

Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions,
normal cellular growth, differentiation and function. Mammalian brain cells cannot …

Although the mechanism of riboflavin (RF) intestinal uptake has been the subject of many
studies, virtually nothing is known about the cellular regulation of the uptake process. In the …