Paclitaxel-loaded polyester nanoparticles prepared by spray-drying technology: in vitro bioactivity evaluation
P López-Gasco, I Iglesias, J Benedí… - Journal of …, 2011 - Taylor & Francis
Paclitaxel (PTX), an antimicrotubular agent used in the treatment of ovarian and breast
cancer, was encapsulated in nanoparticles (NPs) of poly (lactide-co-glycolide)(PLGA) and …
cancer, was encapsulated in nanoparticles (NPs) of poly (lactide-co-glycolide)(PLGA) and …
Advances of paclitaxel formulations based on nanosystem delivery technology
In this paper, an overview of recent advances of paclitaxel formulations based on
nanosystems is provided. Paclitaxel is very effective in the treatment of various cancers …
nanosystems is provided. Paclitaxel is very effective in the treatment of various cancers …
Preparation and characterization of polymeric pH-sensitive STEALTH® nanoparticles for tumor delivery of a lipophilic prodrug of paclitaxel
BB Lundberg - International journal of pharmaceutics, 2011 - Elsevier
Paclitaxel is an effective and widely used anti-cancer agent. However, the drug is difficult to
formulate for parenteral administration because of its low water solubility and Cremophor …
formulate for parenteral administration because of its low water solubility and Cremophor …
Papain decorated multi‐functional polymeric micelles for the targeted intracellular delivery of paclitaxel
Mucopermeating nanocargoes being able to overcome mucosal, as well as extracellular
barrier leads to enhance penetration of poorly soluble anticancer drugs at its target site. We …
barrier leads to enhance penetration of poorly soluble anticancer drugs at its target site. We …
A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer
Paclitaxel (PTX) is one of the most effective chemotherapeutic drugs for the treatment of a
variety of cancers. However, it is associated with serious side effects caused by PTX itself …
variety of cancers. However, it is associated with serious side effects caused by PTX itself …
Development and evaluation of transferrin-stabilized paclitaxel nanocrystal formulation
The aim of the present study was to prepare and evaluate a paclitaxel nanocrystal-based
formulation stabilized by serum protein transferrin in a non-covalent manner. The pure …
formulation stabilized by serum protein transferrin in a non-covalent manner. The pure …
Architectural layer-by-layer assembly of drug nanocapsules with PEGylated polyelectrolytes
TG Shutava, PP Pattekari, KA Arapov, VP Torchilin… - Soft Matter, 2012 - pubs.rsc.org
150–200 nm diameter capsules containing 60–70 wt% of poorly soluble drugs, paclitaxel
and camptothecin, were produced by layer-by-layer (LbL) assembly on drug nanocores in a …
and camptothecin, were produced by layer-by-layer (LbL) assembly on drug nanocores in a …
Nanoparticle-based biocompatible and targeted drug delivery: characterization and in vitro studies
X Yu, MV Pishko - Biomacromolecules, 2011 - ACS Publications
Paclitaxel nanoparticles (PAX NPs) prepared with the size of 110±10 nm and ζ potential of−
40±3 mV were encapsulated in synthetic/biomacromolecule shell chitosan, dextran-sulfate …
40±3 mV were encapsulated in synthetic/biomacromolecule shell chitosan, dextran-sulfate …
Direct comparison of two albumin-based paclitaxel-loaded nanoparticle formulations: is the crosslinked version more advantageous?
C Li, Y Li, Y Gao, N Wei, X Zhao, C Wang, Y Li… - International journal of …, 2014 - Elsevier
Nanoparticles using albumin as particle matrix have entered the mainstream of drug
delivery. It was reported that non-crosslinked albumin nanoparticles were unstable in …
delivery. It was reported that non-crosslinked albumin nanoparticles were unstable in …
Characterization and preparation of core–shell type nanoparticle for encapsulation of anticancer drug
MK Jang, YI Jeong, JW Nah - Colloids and Surfaces B: Biointerfaces, 2010 - Elsevier
The aim of this study is to prepare delivery vehicles of paclitaxel using low molecular weight
water-soluble chitosan (LMWSC) and evaluate them as an anticancer drug delivery system …
water-soluble chitosan (LMWSC) and evaluate them as an anticancer drug delivery system …