Paclitaxel-loaded polyester nanoparticles prepared by spray-drying technology: in vitro bioactivity evaluation

P López-Gasco, I Iglesias, J Benedí… - Journal of …, 2011 - Taylor & Francis
Paclitaxel (PTX), an antimicrotubular agent used in the treatment of ovarian and breast
cancer, was encapsulated in nanoparticles (NPs) of poly (lactide-co-glycolide)(PLGA) and …

Advances of paclitaxel formulations based on nanosystem delivery technology

C Luo, Y Wang, Q Chen, X Han, X Liu… - Mini Reviews in …, 2012 - ingentaconnect.com
In this paper, an overview of recent advances of paclitaxel formulations based on
nanosystems is provided. Paclitaxel is very effective in the treatment of various cancers …

Preparation and characterization of polymeric pH-sensitive STEALTH® nanoparticles for tumor delivery of a lipophilic prodrug of paclitaxel

BB Lundberg - International journal of pharmaceutics, 2011 - Elsevier
Paclitaxel is an effective and widely used anti-cancer agent. However, the drug is difficult to
formulate for parenteral administration because of its low water solubility and Cremophor …

Papain decorated multi‐functional polymeric micelles for the targeted intracellular delivery of paclitaxel

S Razzaq, A Rauf, A Raza, TA Tabish… - Polymers for …, 2021 - Wiley Online Library
Mucopermeating nanocargoes being able to overcome mucosal, as well as extracellular
barrier leads to enhance penetration of poorly soluble anticancer drugs at its target site. We …

A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer

K Xiao, J Luo, WL Fowler, Y Li, JS Lee, L Xing… - Biomaterials, 2009 - Elsevier
Paclitaxel (PTX) is one of the most effective chemotherapeutic drugs for the treatment of a
variety of cancers. However, it is associated with serious side effects caused by PTX itself …

Development and evaluation of transferrin-stabilized paclitaxel nanocrystal formulation

Y Lu, Z Wang, T Li, H McNally, K Park… - Journal of Controlled …, 2014 - Elsevier
The aim of the present study was to prepare and evaluate a paclitaxel nanocrystal-based
formulation stabilized by serum protein transferrin in a non-covalent manner. The pure …

Architectural layer-by-layer assembly of drug nanocapsules with PEGylated polyelectrolytes

TG Shutava, PP Pattekari, KA Arapov, VP Torchilin… - Soft Matter, 2012 - pubs.rsc.org
150–200 nm diameter capsules containing 60–70 wt% of poorly soluble drugs, paclitaxel
and camptothecin, were produced by layer-by-layer (LbL) assembly on drug nanocores in a …

Nanoparticle-based biocompatible and targeted drug delivery: characterization and in vitro studies

X Yu, MV Pishko - Biomacromolecules, 2011 - ACS Publications
Paclitaxel nanoparticles (PAX NPs) prepared with the size of 110±10 nm and ζ potential of−
40±3 mV were encapsulated in synthetic/biomacromolecule shell chitosan, dextran-sulfate …

Direct comparison of two albumin-based paclitaxel-loaded nanoparticle formulations: is the crosslinked version more advantageous?

C Li, Y Li, Y Gao, N Wei, X Zhao, C Wang, Y Li… - International journal of …, 2014 - Elsevier
Nanoparticles using albumin as particle matrix have entered the mainstream of drug
delivery. It was reported that non-crosslinked albumin nanoparticles were unstable in …

Characterization and preparation of core–shell type nanoparticle for encapsulation of anticancer drug

MK Jang, YI Jeong, JW Nah - Colloids and Surfaces B: Biointerfaces, 2010 - Elsevier
The aim of this study is to prepare delivery vehicles of paclitaxel using low molecular weight
water-soluble chitosan (LMWSC) and evaluate them as an anticancer drug delivery system …