Abstract Hydroquinone (HQ), a well-known anti-hyperpigmentation agent suffers from (a)
instability due to rapid oxidation,(b) insufficient skin penetration because of hydrophilic …

Kojic acid (KA) as tyrosinase inhibitor shows insufficient skin penetration and several
adverse events due topical administration. KA solid lipid nanoparticles (KA-SLNs) were …

Purpose: Hyperpigmentation occurs when melanin is overproduced in certain spots on the
skin and is one of the most challenging skin conditions to treat. Although it is usually …

Nanostructured lipid carrier (NLC) was prepared by homogenization emulsification method
and improved with modified surfactants. The properties of nanoparticles were investigated …

Cutaneous hyperpigmentation is a widespread pathology affecting a large slice of the world
population. In this work, we propose a treatment approach based on the co-delivery of 4 …

This study was aimed at preparing and characterising kojic acid nanostructured lipid carriers
(KA-NLCs) for delivery to skin. KA-NLCs were prepared using high-speed homogenization …

Sažetak Coenzyme Q10 (Q10) loaded solid lipid nanoparticles (SLN) were prepared by the
high speed homogenization method and incorporated into Carbopol 974P hydrogels …

Hydroxyzine HCL (HHCL) is an antihistamine, used for the treatment of allergic skin
conditions. The purpose of this study was to achieve a dual phase drug delivery rate across …

The present study was to formulate and optimize Thymoquinone (TQ) lipid nanoparticles
(NPs) formulations for the treatment of psoriasis. The formulation optimization was …

The clinical use of halobetasol propionate (HP) is related to some adverse effects like
irritation, pruritus and stinging. The purpose of this work was to construct HP-loaded solid …