Stroke is a group of diseases resulting from cerebral vascular rupture or obstruction and
subsequent brain blood circulation disorder, leading to rapid neurological deficits. Ischemic …

Cerebral inflammation and apoptotic cell death are two processes implicated in the
progressive tissue damage that occurs following traumatic brain injury (TBI), and strategies …

Minocycline is a member of the tetracycline class of molecules with broad-spectrum
antibiotic activity. The unique properties of minocycline result in increased tissue distribution …

Minocycline is a broad-spectrum tetracycline antibiotic. A number of preclinical studies have
shown that minocycline exhibits neuroprotective effects in various animal models of …

The neuroprotective effects of minocycline–which is broadly protective in neurologic-disease
models featuring cell death and is being evaluated in clinical trials–were investigated both in …

Background There are no drugs presently available to treat traumatic brain injury (TBI). A
variety of single drugs have failed clinical trials suggesting a role for drug combinations …

Minocycline is a widely used tetracycline antibiotic. For decades, it has been used to treat
various gram‐positive and gram‐negative infections. Minocycline was recently shown to …

To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal
models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and …

Background The effects of minocycline on neuronal injury after spinal cord injury (SCI) are
limited and controversial. Therefore we aimed to investigate the protective effects of …

Minocycline, an antibiotic of the tetracycline family, has been shown to display
neurorestorative or neuroprotective properties in various models of neurodegenerative …