Background: An increasing pattern of fluoroquinolone resistance (FQR) among bacterial
pathogens has been described worldwide. In this study, we compared the patterns of …

Plasmid-mediated quinolone resistance (PMQR) determinants and the distribution of
mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC were …

Introduction: Resistance to fluoroquinolones is mainly due to point mutations that gave rise
to amino acid substitutions in the quinolone resistance-determining regions of either gyrA or …

Resistance to fluoroquinolones (FQ) is being increasingly reported and found to be
mediated by efflux pumps, plasmid-mediated quinolone resistance genes (PMQR) and …

Fluoroquinolones (FQs) resistance due to their extensive clinical use has been a major
problem in clinical settings that lead to limitation of treatment. This study aimed to investigate …

OBJECTIVE: To determine whether plasmid-mediated quinolone resistance (PMQR)
determinants play a role in the increasing resistance to fluoroquinolones among Escherichia …

Background Quinolone resistance (QR) is one component of the MDR emerging in
Escherichia coli and is of particular concern given the widespread use of fluoroquinolones …

The high frequency of fluoroquinolone resistance in Escherichia coli is a feature of clinical
bacteriology in China, where the molecular epidemiology and genetic characteristics of this …

Methods: Forty three isolates of E. coli obtained from patients with extra-intestinal infections
were subjected to antibiogram to detect fluoroquinolone resistance. The mechanism of …

Plasmid-mediated quinolone resistance (PMQR) determinants combined with mutations in
quinolone resistance-determining regions (QRDRs) and clonal dissemination were …