Thrombolytic therapy is an important therapeutic intervention in a variety of clinical
conditions associated with thrombosis of arteries or veins. Since the first trial was published …

Thrombolytic therapy is an essential tool in the array of therapies designed to reopen
arteries and veins occluded with thrombus. As the use of thrombolytic agents has entered …

Since the first trial was published in 1959 (1), thrombolytic therapy has evolved to become
an important therapeutic option for patients with ar-terial and venous thrombosis. Although …

Thrombolytic therapy represents part of a conjoint approach to achieving vascular
reperfusion, based primarily on the use of fibrinolytic agents delivered systemically or …

The main indications for thrombolytic therapy are acute myocardial infarction and severe
pulmonary embolism. Anecdotally, thrombolytic therapy is also used in patients with …

• Despite the discovery of thrombolytic agents more than 50 years ago, only recently has
major interest become evident in their use to treat myocardial infarction, venous …

Thrombolytics are successful for dissolving thrombi in any vessel, but clinical benefit varies
according to the involved organ or limb (1, 2). Considering the gamut of possibilities, from a …

ALTHOUGH many details of the process of thrombogenesis are unclear, it is generally
thought that it involves both platelet activity (adhesion and aggregation) and fibrin formation …

The accepted role for thrombolytic therapy has until recently been limited because of its
complexity and side-effects. It has generally been reserved for use systemically in a limited …

Rationale for the use of thrombolytic therapy is based on the fact that thrombolytic agents
induce the dissolution of preformed pathologic thrombi and emboli. This feat is not …