Cardiovascular disease remains the main cause of death worldwide. For this reason,
strategies for the primary prevention of atherosclerosis and atherosclerosis-related …

Platelets play important roles in thrombosis-dependent obstructive cardiovascular diseases.
In addition, it has now become evident that platelets also participate in the earliest stages of …

Beyond their role in hemostasis and thrombosis platelets are critically involved in the onset
of atherosclerosis. Platelets represent an important linkage between inflammation, and …

Platelets, crucial mediators of the acute complications of atherosclerosis that cause life-
threatening ischemic events at late stages of the disease, are also key effectors of …

Cardiovascular diseases are one of the leading causes of morbidity and mortality in
industrialized countries, and although many processes play a role in the development of …

Platelets have evolved highly specialized adhesion mechanisms that enable cell-matrix and
cell-cell interactions throughout the entire vasculature irrespective of the prevailing …

The crucial role of platelets in primary hemostasis and repair of injured endothelium is well
established, as is their role in atherothrombosis. No other single cell type is responsible for …

Platelets are small, anucleate blood elements of critical importance in cardiovascular
disease. The ability of platelets to activate and aggregate to form blood clots in response to …

Several studies suggest an important role for platelets in atherogenesis, not only as
mediators of thrombus formation, but also as inducers of inflammation. Several lines of …

Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …