Outbred Sprague-Dawley rats selectively bred for their propensity to develop diet-induced
obesity (DIO) become heavier on low-fat diet than those bred to be diet resistant (DR) …

Among outbred Sprague-Dawley rats, approximately one-half develop diet-induced obesity
(DIO) and one-half are diet resistant (DR) on a diet relatively high in fat and energy content …

In rats selectively bred to develop diet-induced obesity (DIO) or to be diet-resistant (DR), DIO
maternal obesity selectively enhances the development of obesity and insulin resistance in …

Previous breeding for the diet-induced obese (DIO) trait from outbred Sprague-Dawley rats
produced a substrain with selection characteristics suggesting a polygenic mode of …

In outbred Sprague-Dawley rats, about one-half develop diet-induced obesity (DIO) on a diet
relatively high in fat and energy (HE diet). The rest are diet resistant (DR), gaining weight …

Rats selectively bred to develop diet-induced obesity (DIO) were compared with those bred
to be diet resistant (DR) on a 31% fat high-energy diet with regard to their central leptin …

Because rearing rats in large litters (LLs) protects them from becoming obese, we postulated
that LL rearing would protect rats selectively bred to develop diet-induced obesity (DIO) from …

In rats selectively bred to develop diet-induced obesity (DIO) 3 wk of postweaning exercise
reduces weight and adipose regain for 10 wk after exercise cessation, despite intake of 31 …

Rats selectively bred to develop diet-induced obesity (DIO) spontaneously gain more body
weight between 5 and 7 wk of age than do those bred to be diet resistant (DR). Here, chow …

Half of Sprague-Dawley rats develop and defend diet-induced obesity (DIO) or diet
resistance (DR) when fed a high-energy (HE) diet. Here, adult male rats were made DIO or …