The staphylococcal biofilm-based infections of wounds still pose a significant therapeutical
challenge. Treated improperly, they increase the risk of limb amputation or even death of the …

Aims Although several factors contribute to wound healing, bacterial infections and the
presence of biofilm can significantly affect healing. Despite that this clearly indicates that …

Increasing data suggesting that microorganisms in the biofilm form are among the leading
agents of persistent infections of chronic wounds require the development of new …

Biofilms are one of the greatest challenges in today's treatment of chronic wounds. While
antimicrobials kill platonic bacteria within seconds, they are rarely able to harm biofilms. In …

Chronic wounds are a large burden to patients and healthcare systems. Biofilm infections in
chronic wounds are crucial factors leading to non‐healing of wounds. It is important to study …

In the development of antimicrobial agents, the use of both in-vitro and in-vivo models is
essential for successful outcomes. In-vitro tests are necessary to help determine initial dose …

Biofilm formation is an important virulence factor that allows bacteria to resist host responses
and antibacterial agents. The aim of the study was to assess the in vitro activities of several …

Staphylococcal biofilms are major causative factors of non-healing wound infections. Their
treatment algorithms recommend the use of locally applied antiseptic agents to counteract …

The increasing incidence of non-healing wounds constitutes a pivotal socio-economic
burden. 60–80% of chronic wounds are colonized by pathogenic microorganisms within a …

It is known for roughly a decade that bacterial communities (called biofilms) are responsible
for significant enhanced antibiotherapy resistance. Biofilms are involved in tissue persistent …