Volatile organic compounds in breath as markers for irritable bowel syndrome: a metabolomic approach

A Baranska, Z Mujagic, A Smolinska… - Alimentary …, 2016 - Wiley Online Library
Background The diagnosis of irritable bowel syndrome (IBS) is challenging because of its
heterogeneity and multifactorial pathophysiology. No reliable biomarkers of IBS have been …

Volatile organic compound profiling as a potential biomarker in irritable bowel syndrome: A feasibility study

K Van Malderen, N Hanning, H Lambrechts… - Frontiers in …, 2022 - frontiersin.org
Background Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder for which
no diagnostic tools are currently available. Patients are diagnosed using the Rome IV …

Volatile organic compounds as potential biomarkers of irritable bowel syndrome: A systematic review

VRY Zhang, GK Ramachandran… - …, 2023 - Wiley Online Library
Background Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disease
characterized by intermittent abdominal pain with altered bowel habits. Due to the …

An investigation of fecal volatile organic metabolites in irritable bowel syndrome

I Ahmed, R Greenwood, BL Costello, NM Ratcliffe… - PloS one, 2013 - journals.plos.org
Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to
invasive investigations in order to rule out other diseases and reassure their patients …

A distinct colon-derived breath metabolome is associated with inflammatory bowel disease, but not its complications

F Rieder, S Kurada, D Grove, F Cikach… - Clinical and …, 2016 - journals.lww.com
OBJECTIVES: The accuracy of available noninvasive biomarkers for diagnosis, stratification,
and prediction of inflammatory bowel disease (IBD) courses is limited. We analyzed volatile …

Volatomics in inflammatory bowel disease and irritable bowel syndrome

K Van Malderen, BY De Winter, G Joris… - …, 2020 - thelancet.com
Volatile organic compounds (VOCs) are produced by the human metabolism, inflammation
and gut microbiota and form the basis of innovative volatomics research. VOCs detected …

Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and …

AH Keshteli, KL Madsen, R Mandal… - Alimentary …, 2019 - Wiley Online Library
Background Evaluation of the metabolomic profile of patients with irritable bowel syndrome
offers an opportunity to identify novel pathophysiological targets and biomarkers that could …

[HTML][HTML] Biomarkers of irritable bowel syndrome

JH Kim, E Lin, M Pimentel - Journal of neurogastroenterology and …, 2017 - ncbi.nlm.nih.gov
Traditionally, irritable bowel syndrome (IBS) has not been regarded as an organic disease,
and the pathophysiology of IBS is heterogeneous. Currently, the diagnosis of IBS is based …

Volatile organic compounds in exhaled air as novel marker for disease activity in Crohn's disease: a metabolomic approach

AGL Bodelier, A Smolinska, A Baranska… - Inflammatory bowel …, 2015 - academic.oup.com
Background Disappearance of macroscopic mucosal inflammation predicts long-term
outcome in Crohn's disease (CD). It can be assessed by ileocolonoscopy, which is …

Volatile organic compounds in feces associate with response to dietary intervention in patients with irritable bowel syndrome

M Rossi, R Aggio, HM Staudacher, MC Lomer… - Clinical …, 2018 - Elsevier
Background & Aims Dietary interventions are effective in management of patients with
irritable bowel syndrome (IBS), although responses vary. We investigated whether fecal …