Osteoarthritis (OA) is considered to be a complex illness in which the tissues of the joint play
a significant role in the initiation and/or progression of the pathophysiology. We still do not …

ALTHOUGH major progress has been made in the last few years, there is still much to learn
about the etiology, pathogenesis and progression of osteoarthritis (OA). This disease can be …

The classical view of the pathogenesis of osteoarthritis (OA) is that subchondral sclerosis is
associated with, and perhaps causes, age-related joint degeneration. Recent observations …

The subchondral bone is involved in the pathophysiology of osteoarthritis (OA), both by
biochemical and mechanical pathways. Overloaded OA subchondral bone osteoblasts …

These findings have an immediate implication for research because new tools need to be
developed to study the subchondral bone–cartilage functional unit. Moreover, it could lead …

Osteoarthritis (OA) is a degenerative bone disease associated with aging. The rising global
aging population has led to a surge in OA cases, thereby imposing a significant …

Osteoarthritis is a whole joint disease characterised by the disappearance of the cartilage
associated with subchondral bone sclerosis, formation of osteophytes and a mild …

Osteoarthritis (OA) is a slowly progressive degenerative joint disorder characterized by
cartilage damage, changes in periarticular bone including osteophyte formation and a …

Osteoarthritis (OA) is a major cause of disability in the adult population. As a progressive
degenerative joint disorder, OA is characterized by cartilage damage, changes in the …

Arthritis is the most frequently diagnosed chronic medical condition worldwide. Osteoarthritis
accounts for 40 to 60% of degenerative illnesses of the musculoskeletal system. On the …