[HTML][HTML] Genetics in idiopathic pulmonary fibrosis pathogenesis, prognosis, and treatment

A Kaur, SK Mathai, DA Schwartz - Frontiers in medicine, 2017 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia (IIP), is characterized by irreversible scarring of the lung parenchyma and …

Genetics of idiopathic pulmonary fibrosis: from mechanistic pathways to personalised medicine

P Spagnolo, V Cottin - Journal of medical genetics, 2017 - jmg.bmj.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and ultimately fatal disorder for
which there is no cure. While the disease is by definition idiopathic, accumulating evidence …

The genetic basis of idiopathic pulmonary fibrosis

JA Kropski, TS Blackwell… - European Respiratory …, 2015 - Eur Respiratory Soc
Throughout the past decade, there have been substantial advances in understanding the
pathogenesis of idiopathic pulmonary fibrosis (IPF). Recently, several large genome-wide …

Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis

KC Meyer - Expert review of respiratory medicine, 2017 - Taylor & Francis
Introduction: Many forms of interstitial lung disease (ILD) can progress to extensive fibrosis
and respiratory failure. Idiopathic pulmonary fibrosis (IPF), which generally has a poor …

Beyond the diagnosis of idiopathic pulmonary fibrosis; the growing role of systems biology and stratified medicine

TM Maher - Current Opinion in Pulmonary Medicine, 2013 - journals.lww.com
Use of molecular research techniques in large populations of well-phenotyped patients is
leading to major advances in understanding of IPF. As new treatments for IPF emerge, it is to …

[HTML][HTML] Idiopathic pulmonary fibrosis is a complex genetic disorder

DA Schwartz - Transactions of the American Clinical and …, 2016 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a complex, heterogeneous genetic disorder that is
associated with rare and common sequence variants in many genes (MUC5B, SFTPC …

Genetics in pulmonary fibrosis—familial cases provide clues to the pathogenesis of idiopathic pulmonary fibrosis

WE Lawson, JE Loyd, AL Degryse - The American journal of the medical …, 2011 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is the most common form of the idiopathic interstitial
pneumonias and remains a disease with a poor prognosis. Familial interstitial pneumonia …

[HTML][HTML] Idiopathic pulmonary fibrosis: epidemiology, natural history, phenotypes

J Sauleda, B Núñez, E Sala, JB Soriano - Medical Sciences, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial
pneumonias. It is characterized by a chronic, progressive, fibrotic interstitial lung disease of …

Pathogenesis of idiopathic pulmonary fibrosis

PJ Wolters, HR Collard, KD Jones - Annual Review of Pathology …, 2014 - annualreviews.org
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

What we know about the pathogenesis of idiopathic pulmonary fibrosis

S Puglisi, SE Torrisi, R Giuliano… - … in respiratory and …, 2016 - thieme-connect.com
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown cause,
occurring in adults, limited to the lungs and associated with the pathologic and radiologic …