In α-chloralose-anesthetized rats, changes in the blood oxygenation level-dependent
(BOLD) functional MRI (fMRI) signal (ΔS/S), and the relative spiking frequency of a neuronal …

Introduction 2883. Relationship between neuroenergetics and neurotransmitter flux 2944. A
model of coupling between neuroenergetics and neurotransmission 2965. Relationship …

Functional MRI (fMRI) is widely assumed to measure neuronal activity, but no satisfactory
mechanism for this linkage has been identified. Here we derived the changes in the …

This study reports the first measurement of the relative cerebral metabolic rate of oxygen
utilization (rCMRO2) during functional brain activation with sufficient temporal resolution to …

In recent years, cognitive neuroscientists have taken great advantage of functional magnetic
resonance imaging (fMRI) as a non-invasive method of measuring neuronal activity in the …

Understanding the link between the hemodynamic response and the underlying neuronal
activity is important for interpreting functional magnetic resonance (fMRI) signals in human …

Energetics of resting and evoked fMRI signals were related to localized ensemble firing
rates (ν) measured by electrophysiology in rats. Two different unstimulated, or baseline …

The complex activities of the brain need not distract us from the certainty that it uses energy
and performs work very efficiently. The human brain, which claims∼ 2% of our body mass, is …

The conventional functional MRI (fMRI) map offers information indirectly about localized
changes in neuronal activity because it reflects changes in blood oxygenation, not actual …

Functional neuroimaging measures quantitative changes in neurophysiological parameters
coupled to neuronal activity during observable behavior. These results have usually been …