Background The value of quantitative CT (QCT) to identify chronic obstructive pulmonary
disease (COPD) phenotypes is increasingly appreciated. The authors hypothesised that …

EvA (Emphysema versus Airway disease) is a multicentre project to study mechanisms and
identify biomarkers of emphysema and airway disease in chronic obstructive pulmonary …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that is
characterized by chronic airflow limitation. Unraveling of this heterogeneity is challenging …

ABSTRACT COPD is a heterogeneous disorder with clinical assessment becoming
increasingly multidimensional. We hypothesized HRCT phenotype would strongly influence …

Computed tomographic based indices of emphysematous lung destruction may highlight
differences in disease pathogenesis and further enable the classification of subjects with …

Background CT scan measures of emphysema and airway disease have been correlated
with lung function in cohorts of subjects with a range of COPD severity. The contribution of …

Purpose To test the hypothesis—given the increasing emphasis on quantitative computed
tomographic (CT) phenotypes of chronic obstructive pulmonary disease (COPD)—that a …

Background COPD is a heterogeneous disease characterized by airflow obstruction and
diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in …

Purpose To correlate currently available quantitative CT measurements for airway disease
with physiological indices and the body-mass index, airflow obstruction, dyspnea, and …

Background COPD is a complex, heterogeneous disease characterised by progressive
development of airflow limitation. Spirometry provides little information about key aspects of …