Identification of natural compounds which inhibit biofilm formation in clinical isolates of Klebsiella pneumoniae

H Magesh, A Kumar, A Alam, U Sekar - 2013 - nopr.niscpr.res.in
Klebsiella pneumoniae, an important opportunistic pathogen, exists as a biofilm in persistent
infections and in-dwelling medical devices. With the objective of identifying natural …

[HTML][HTML] Anti-Biofilm and Associated Anti-Virulence Activities of Selected Phytochemical Compounds against Klebsiella pneumoniae

IJ Adeosun, IT Baloyi, S Cosa - Plants, 2022 - mdpi.com
The ability of Klebsiella pneumoniae to form biofilm renders the pathogen recalcitrant to
various antibiotics. The difficulty in managing K. pneumoniae related chronic infections is …

Antioxidant and antibacterial study of 10 flavonoids revealed rutin as a potential antibiofilm agent in Klebsiella pneumoniae strains isolated from hospitalized patients

Z Wang, Z Ding, Z Li, Y Ding, F Jiang, J Liu - Microbial pathogenesis, 2021 - Elsevier
The emergence of multidrug resistance (MDR) and extensive drug resistance (XDR) in
Klebsiella pneumoniae strains has posed great threats to conventional antibiotics. Previous …

Combination of essential oil and ciprofloxacin to inhibit/eradicate biofilms in multidrug‐resistant Klebsiella pneumoniae

SH Mohamed, MSM Mohamed… - Journal of applied …, 2018 - academic.oup.com
Aim This study aimed to test biofilm inhibition activities of each of essential oils (EOs), main
compounds of EOs and enzymes against pathogenic Klebsiella pneumoniae. Methods and …

Benzoic acid derivatives as potent antibiofilm agents against Klebsiella pneumoniae biofilm

A Rohatgi, P Gupta - Journal of bioscience and bioengineering, 2023 - Elsevier
Klebsiella pneumoniae is responsible for a significant proportion of human urinary tract
infections, and its biofilm is a major virulence. One potential approach to controlling biofilm …

Synergistic Antibiofilm Efficacy of Thymol and Piperine in Combination with Three Aminoglycoside Antibiotics against Klebsiella pneumoniae Biofilms

B Bisso Ndezo, CR Tokam Kuaté… - Canadian Journal of …, 2021 - Wiley Online Library
Background. Thymol and piperine are two naturally occurring bioactive compounds with
several pharmacological activities. In this study, their antibiofilm potential either alone or in …

[HTML][HTML] Evaluation of biofilm formation among Klebsiella pneumoniae isolates and molecular characterization by ERIC-PCR

K Seifi, H Kazemian, H Heidari… - Jundishapur journal …, 2016 - ncbi.nlm.nih.gov
Background: Klebsiella pneumoniae is among the most frequently recovered etiologic
agents from nosocomial infections. This opportunistic pathogen can generate a thick layer of …

Investigation of Antibiotic Resistance and Biofilm Formation in Clinical Isolates of Klebsiella pneumoniae

K Karimi, O Zarei, P Sedighi, M Taheri… - International Journal …, 2021 - Wiley Online Library
Aim. Klebsiella pneumoniae (K. pneumoniae) is an encapsulated Gram‐negative bacterium
that can lead to 14–20% of nosocomial infections. The ability of biofilm formation in this …

Antibiofilm activity of papain enzyme against pathogenic Klebsiella pneumoniae

SH Mohamed, MSM Mohamed, MS Khalil… - Journal of Applied …, 2018 - japsonline.com
Infections caused by biofilm-embedded pathogens decrease the efficacy of traditional
treatments and increase antibiotic tolerance. Most of the human bacterial infections are …

[HTML][HTML] Biofilm formation and antibiotic resistance of Klebsiella pneumoniae isolated from clinical samples in a tertiary care hospital, Klaten, Indonesia

H Nirwati, K Sinanjung, F Fahrunissa, F Wijaya… - BMC proceedings, 2019 - Springer
Background Klebsiella pneumoniae (K. pneumoniae) is a common cause of health-care
associated infections (HAIs) and has high levels of antibiotic resistance. These bacteria are …