Impact of tau on neurovascular pathology in Alzheimer's disease
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most prevalent
cause of dementia. The main cerebral histological hallmarks are represented by …
cause of dementia. The main cerebral histological hallmarks are represented by …
Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease
R Apátiga-Pérez, LO Soto-Rojas… - Metabolic brain …, 2022 - Springer
Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive
functions and short-term memory. AD patients present two distinctive neuropathological …
functions and short-term memory. AD patients present two distinctive neuropathological …
Alzheimer's disease, cerebrovascular disease, and the β-amyloid cascade
K Honjo, SE Black, NPLG Verhoeff - Canadian Journal of …, 2012 - cambridge.org
Alzheimer's disease (AD), considered the commonest neurodegenerative cause of
dementia, is associated with hallmark pathologies including extracellular amyloid-β protein …
dementia, is associated with hallmark pathologies including extracellular amyloid-β protein …
Brain vasculature accumulates tau and is spatially related to tau tangle pathology in Alzheimer's disease
Z Hoglund, N Ruiz-Uribe, E Del Sastre, B Woost… - Acta …, 2024 - Springer
Insoluble pathogenic proteins accumulate along blood vessels in conditions of cerebral
amyloid angiopathy (CAA), exerting a toxic effect on vascular cells and impacting cerebral …
amyloid angiopathy (CAA), exerting a toxic effect on vascular cells and impacting cerebral …
The neurovascular unit dysfunction in Alzheimer's disease
LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
The amyloid-tau-neuroinflammation axis in the context of cerebral amyloid angiopathy
P Cisternas, X Taylor… - International journal of …, 2019 - mdpi.com
Cerebral amyloid angiopathy (CAA) is typified by the cerebrovascular deposition of amyloid.
Currently, there is no clear understanding of the mechanisms underlying the contribution of …
Currently, there is no clear understanding of the mechanisms underlying the contribution of …
[HTML][HTML] Cerebral microvascular accumulation of tau oligomers in Alzheimer's disease and related tauopathies
DL Castillo-Carranza, AN Nilson, CE Van Skike… - Aging and …, 2017 - ncbi.nlm.nih.gov
The importance of vascular contributions to cognitive impairment and dementia (VCID)
associated with Alzheimer's disease (AD) and related neurodegenerative diseases is …
associated with Alzheimer's disease (AD) and related neurodegenerative diseases is …
Progression of Alzheimer's disease, tau propagation, and its modifiable risk factors
S Takeda - Neuroscience research, 2019 - Elsevier
The number of patients with Alzheimer's disease (AD) has been increasing exponentially
side by side with aging societies worldwide. Symptoms of AD worsen over time due to …
side by side with aging societies worldwide. Symptoms of AD worsen over time due to …
Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy
Cerebral amyloid angiopathy (CAA) is typified by the cerebrovascular deposition of amyloid.
Currently, there is no clear understanding of the mechanisms underlying the contribution of …
Currently, there is no clear understanding of the mechanisms underlying the contribution of …
Dissecting the contribution of vascular alterations and aging to Alzheimer's disease
C Janota, CA Lemere, MA Brito - Molecular neurobiology, 2016 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …
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