The enzyme xanthine oxidase has been implicated as a generator of toxic oxygen
metabolites that contribute to ischemic injury. Because substantial species variability has …

Samples from four human hearts were analyzed for both their xanthine dehydrogenase and
xanthine oxidase content. We used the conventional spectrophotometric assay and a more …

The xanthine oxidase pathway has been proposed as a source ofoxygen-derived free
radicals in ischemic and reperfused myocardium. A spectrophotometric assay was …

The enzyme, xanthine oxidase, has become a focus of research activity because of its
proposed role as a source of destructive free radicals in ischaemia reperfusion injury [l]. The …

Oxygen free radicals generated by xanthine oxidase have been implicated in cardiac
damage. The activity of xanthine oxidase/reductase in adult rat heart is considerable. Its …

The enzyme, xanthine oxidase, has been pro osed as. a major source of free radicals
causing tissue lama e in ischaemia reperfusion injury [l]. The relevance ofthis pathogenic …

While the free radical-generating enzyme xanthine oxidase is a central mechanism of injury
in postischemic tissues, questions remain regarding how xanthine oxidase-mediated radical …

The free radical-generating enzyme xanthine oxidase has been hypothesized to be a central
mechanism of the injury which occurs in postischemic tissues; however, its importance …

Myocardial xanthine oxidase has been associated with reoxygenation injury induced by
oxygen radicals. The damage due to myocardial ischemia and reperfusion increases with …

Oxygen derived free radicals have been implicated as mediators of tissue injury in several
disease states. They have been proposed to play a role in the pathology of cerebral …