We measured time course and extent of xanthine dehydrogenase (XD) to xanthine oxidase
(XO) conversion in ischemic human and rat intestine. To model normothermic no-flow …

Reactive oxygen species, in particular superoxide, have been closely linked to the
underlying pathophysiology of ischemic cardiomyopathy: superoxide not only mediates …

Reactive oxygen metabolites generated from xanthine oxidase play an important role in the
pathogenesis of ischemia-induced tissue injury. In a hemorrhagic shock model of ischemia …

✓ Xanthine oxidase activity in the rat brain was measured by means of high-performance
liquid chromatography with electrochemical detection of uric acid. Cerebral ischemia was …

The molybdoenzyme, xanthine oxidoreductase is a homodimer of 150 kDa subunits. It has
wide substrate specificity but is best known for its capacity to oxidise hypoxanthine to …

The enzyme xanthine oxidoreductase (XOR) is an important source of oxygen free radicals
and related postischemic injury. Xanthine dehydrogenase (XDH), the major form of XOR in …

Activity of xanthine oxidoreductase (total xanthine dehydrogenase plus xanthine oxidase)
and xanthine oxidase was determined cytophotometrically in periportal and pericentral …

Xanthine oxidase has been hypothesized to be an important source of biological free radical
generation. The enzyme generates the superoxide radical,• O 2− and has been widely …

Localization of the activity of both the dehydrogenase and oxidase forms of xanthine
oxidoreductase were studied in biopsy and postmortem specimens of various human tissues …

Oxygen radicals have been proposed to be involved in the induction of liver cell damage
during reperfusion after ischemia. The role of xanthine oxidase in this process and the …