Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Chronic kidney disease: effects on the cardiovascular system

EL Schiffrin, ML Lipman, JFE Mann - Circulation, 2007 - Am Heart Assoc
Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic
kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the …

Targeting vascular calcification in chronic kidney disease

AJ Nelson, P Raggi, M Wolf, AM Gold… - Basic to Translational …, 2020 - jacc.org
Cardiovascular (CV) disease remains an important cause of morbidity and mortality for
patients with chronic kidney disease (CKD). Although clustering of traditional risk factors with …

[HTML][HTML] The interplay between mineral metabolism, vascular calcification and inflammation in Chronic Kidney Disease (CKD): challenging old concepts with new facts

C Viegas, N Araújo, C Marreiros, D Simes - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) is one of the most powerful predictors of premature
cardiovascular disease (CVD), with heightened susceptibility to vascular intimal and medial …

Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options

J Jankowski, J Floege, D Fliser, M Böhm, N Marx - Circulation, 2021 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …

Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle?

P Stenvinkel, J Jesu, J Axelsson… - Clinical journal of the …, 2008 - journals.lww.com
Premature cardiovascular disease (CVD), including stroke, peripheral vascular disease,
sudden death, coronary artery disease, and congestive heart failure, is a notorious problem …

Oxidative stress–chronic kidney disease–cardiovascular disease: A vicious circle

V Ravarotto, F Simioni, E Pagnin, PA Davis, LA Calò - Life sciences, 2018 - Elsevier
Chronic kidney disease patient's progression to end-stage renal disease as well as their
high mortality are linked to cardiovascular disease. However, the high incidence rate of …

The impact of uremic toxins on vascular smooth muscle cell function

L Hénaut, A Mary, JM Chillon, S Kamel, ZA Massy - Toxins, 2018 - mdpi.com
Chronic kidney disease (CKD) is associated with profound vascular remodeling, which
accelerates the progression of cardiovascular disease. This remodeling is characterized by …

Mechanistic insights into CKD-MBD-related vascular calcification and its clinical implications

R Kaur, R Singh - Life Sciences, 2022 - Elsevier
Abstract Chronic Kidney Disease (CKD) is linked to a rising prevalence of morbidity and
mortality primarily from cardiovascular complications and is considered a high or very high …

Chronic kidney disease and vascular remodelling: molecular mechanisms and clinical implications

M Briet, KD Burns - Clinical science, 2012 - portlandpress.com
CKD (chronic kidney disease) is a severe and complex disease with a very high prevalence
of CV (cardiovascular) complications. CKD patients are exposed to haemodynamic …