Chronic kidney disease and vascular remodelling: molecular mechanisms and clinical implications

M Briet, KD Burns - Clinical science, 2012 - portlandpress.com
CKD (chronic kidney disease) is a severe and complex disease with a very high prevalence
of CV (cardiovascular) complications. CKD patients are exposed to haemodynamic …

Accelerated vascular aging in chronic kidney disease: the potential for novel therapies

S Hobson, S Arefin, A Witasp, L Hernandez… - Circulation …, 2023 - Am Heart Assoc
The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …

Kidney in early atherosclerosis

AR Chade, A Lerman, LO Lerman - Hypertension, 2005 - Am Heart Assoc
Atherosclerosis represents one of the major causes of premature death in the United States
today, and it is frequently associated with, exacerbates, and is aggravated by chronic kidney …

Chronic kidney disease: strategies to retard progression

MT Yan, CT Chao, SH Lin - International journal of molecular sciences, 2021 - mdpi.com
Chronic kidney disease (CKD), defined as the presence of irreversible structural or
functional kidney damages, increases the risk of poor outcomes due to its association with …

Chronic kidney disease and disproportionally increased cardiovascular damage: does oxidative stress explain the burden?

A Duni, V Liakopoulos… - Oxidative medicine …, 2017 - Wiley Online Library
Chronic kidney disease (CKD) patients are among the groups at the highest risk for
cardiovascular disease and significantly shortened remaining lifespan. CKD enhances …

Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications

JM López-Novoa, AB Rodríguez-Peña, A Ortiz… - Journal of translational …, 2011 - Springer
Chronic kidney disease (CKD) comprises a group of pathologies in which the renal
excretory function is chronically compromised. Most, but not all, forms of CKD are …

Epidemiology and mechanisms of uremia-related cardiovascular disease

M Tonelli, SA Karumanchi, R Thadhani - Circulation, 2016 - Am Heart Assoc
Patients with chronic kidney disease and end-stage renal disease are at 5-to 10-fold higher
risk for developing cardiovascular disease (CVD) than age-matched controls. Clinically …

[PDF][PDF] Cardiovascular disease and its relationship with chronic kidney disease.

M Liu, XC Li, L Lu, Y Cao, RR Sun… - European Review for …, 2014 - europeanreview.org
Art. 1.1475/ringraziamenti Page 1 European Review for Medical and Pharmacological Sciences
2918 Abstract. – Cardiovascular disease (CVD), the leading cause of death, is mostly …

[HTML][HTML] Oxidative stress contributes to vascular calcification in patients with chronic kidney disease

M Huang, L Zheng, H Xu, D Tang, L Lin, J Zhang… - Journal of Molecular and …, 2020 - Elsevier
Vascular calcification (VC) is a major cause of mortality in patients with chronic kidney
disease (CKD). While elevations in serum phosphorus contribute to VC, we provide …

Vascular calcification mechanisms: updates and renewed insight into signaling pathways involved in high phosphate-mediated vascular smooth muscle cell …

N Abbasian - Biomedicines, 2021 - mdpi.com
Vascular calcification (VC) is associated with aging, cardiovascular and renal diseases and
results in poor morbidity and increased mortality. VC occurs in patients with chronic kidney …