The International Society of Nephrology has adopted a proactive approach to defining the
current state of kidney care and unmet needs through a multifaceted Closing the Gaps …

Systemic inflammation is a condition intrinsically linked to chronic kidney disease (CKD) and
its other typical sequelae, such as acquired immune dysfunction, protein-energy wasting …

Fibrosis is a process characterized by an excessive accumulation of the extracellular matrix
as a response to different types of tissue injuries, which leads to organ dysfunction. The …

Kidney failure and chronic kidney disease (CKD) are associated with accelerated
cardiovascular disease, apparently because of a high burden of traditional vascular risk …

Despite the improvements in diagnostic tools and medical applications, cardiovascular
diseases (CVD), especially coronary artery disease (CAD), remain the most common cause …

Chronic kidney disease (CKD) is characterized by increased levels of oxidative stress and
inflammation. Oxidative stress and inflammation promote renal injury via damage to …

Patients with chronic kidney disease (CKD) are at a high risk for cardiovascular disease
(CVD), and approximately half of all deaths among patients with CKD are a direct result of …

Cardiovascular complications are the leading cause of death in patients with chronic kidney
disease (CKD). Vascular calcification is a common complication in CKD, and investigators …

Chronic kidney disease (CKD) represents a leading cause of death in the United States.
There is no cure for this disease, with current treatment strategies relying on blood pressure …

It has become apparent that inflammation and inflammatory reactions can evoke renal injury
and promote chronic kidney disease (CKD) progression. Under physiological condition …