Inflammatory responses after ischemic stroke
JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …
tissue repair. This is a complex process involving a range of cell types and effector …
[HTML][HTML] Post-stroke inflammation—target or tool for therapy?
KL Lambertsen, B Finsen, BH Clausen - Acta neuropathologica, 2019 - Springer
Inflammation is currently considered a prime target for the development of new stroke
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …
[HTML][HTML] The local and peripheral immune responses to stroke: implications for therapeutic development
KA Zera, MS Buckwalter - Neurotherapeutics, 2020 - Elsevier
The immune response to stroke is an exciting target for future stroke therapies. Stroke is a
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …
leading cause of morbidity and mortality worldwide, and clot removal (mechanical or …
Targeting the immune system for ischemic stroke
Stroke is responsible for almost 6 million deaths and more than 10% of all mortalities each
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …
year, and two-thirds of stroke survivors remain disabled. With treatments for ischemic stroke …
Filling the gaps on stroke research: Focus on inflammation and immunity
D Levard, I Buendia, A Lanquetin, M Glavan… - Brain, behavior, and …, 2021 - Elsevier
For the last two decades, researchers have placed hopes in a new era in which a
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …
combination of reperfusion and neuroprotection would revolutionize the treatment of stroke …
Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets
JY Kim, M Kawabori, MA Yenari - Current medicinal chemistry, 2014 - ingentaconnect.com
Stroke is a frequent cause of long-term disability and death worldwide. Ischemic stroke is
more commonly encountered compared to hemorrhagic stroke, and leads to tissue death by …
more commonly encountered compared to hemorrhagic stroke, and leads to tissue death by …
Inflammation as therapeutic objective in stroke
Ischemic stroke is the most frequent cause of persistent neurologic disability in modern
Western societies. Albeit it is still not clear whether inflammation is merely an …
Western societies. Albeit it is still not clear whether inflammation is merely an …
Inflammatory responses in brain ischemia
M Kawabori, MA Yenari - Current medicinal chemistry, 2015 - ingentaconnect.com
Brain infarction causes tissue death by ischemia due to occlusion of the cerebral vessels
and recent work has shown that post stroke inflammation contributes significantly to the …
and recent work has shown that post stroke inflammation contributes significantly to the …
Macrophage and monocyte subsets in response to ischemic stroke
N Blank‐Stein, E Mass - European Journal of Immunology, 2023 - Wiley Online Library
Ischemic stroke is a leading cause of disability and mortality. Despite extensive efforts in
stroke research, the only pharmacological treatment currently available is arterial …
stroke research, the only pharmacological treatment currently available is arterial …
[HTML][HTML] Inflammatory mechanisms in ischemic stroke: therapeutic approaches
SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …
most frequent cause of permanent disability in adults worldwide. Despite advances in the …