Lupus progression deteriorates oogenesis quality in MRL/lpr mice

S Delimitreva, G Boneva, I Chakarova… - Immunologic …, 2024 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the
activation of the immune response against self antigens. Numerous reproductive …

Defective oogenesis in mice with pristane-induced model of systemic lupus

SM Delimitreva, GV Boneva, IV Chakarova… - Journal of Reproductive …, 2021 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease
characterized by generation of autoantibodies and severe damage of various organs. The …

[HTML][HTML] A new insight into the impact of systemic lupus erythematosus on oocyte and embryo development as well as female fertility

R Mao, X Wang, R Long, M Wang, L Jin… - Frontiers in …, 2023 - frontiersin.org
Background Systemic lupus erythematosus (SLE) is often associated with adverse
reproductive outcomes. But it's currently unclear regarding the role of SLE in oocyte and …

Skin disease is prevented but nephritis is accelerated by multiple pregnancies in autoimmune MRL/LPR mice

G Kökény, M Godo, E Nagy, M Kardos, K Kotsch… - Lupus, 2007 - journals.sagepub.com
The role of pregnancy in the progression of systemic lupus erythematosus (SLE) is still
poorly understood. We analysed the effect of repeated pregnancies in MRL/lpr mice, a …

Mechanisms behind flare of renal lupus during murine pregnancy

AC Zenclussen, G Kökény, O Thimm… - Reproductive …, 2008 - Elsevier
The outcome of pregnancy in systemic lupus erythematosus is still controversial. The
authors recently reported the disappearance of the manifestation of the skin disease but a …

Reproductive aspects of systemic lupus erythematosus

O Oktem, H Yagmur, H Bengisu, B Urman - Journal of Reproductive …, 2016 - Elsevier
Systemic lupus erythematosus (SLE) is an auto-immune systemic disease showing a strong
predilection for women of reproductive age. Higher prevalance of SLE among young women …

Ovarian function and reproductive outcomes of female patients with systemic lupus erythematosus and the strategies to preserve their fertility

O Oktem, Y Guzel, S Aksoy, E Aydin… - … & gynecological survey, 2015 - journals.lww.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune systemic disease that mainly
affects women of reproductive age. Emerging data from recent molecular studies show us …

Autoimmune abnormality affects ovulation and oocyte-pick-up in MRL/MpJ-Faslpr/lpr mice

M Hosotani, O Ichii, T Nakamura, SO Kanazawa… - Lupus, 2018 - journals.sagepub.com
Ovulation and oocyte-pick-up are essential processes in fertilization. Herein, we found
associations between autoimmune disease and the aforementioned processes in mice. At …

[HTML][HTML] Ovarian function in patients with systemic lupus erythematosus: Pathogenesis, drug application and prospective therapies

M Xu, LL Tian, XL Li, C Bao, HW Zhang… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease in which multiple
organs are damaged that prevails in fertile women. Currently, glucocorticoids and …

[HTML][HTML] Prolactin promotes proliferation of germinal center B cells, formation of plasma cells, and elevated levels of IgG3 anti-dsDNA autoantibodies

R Carreón-Talavera, P Santana-Sánchez… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) mainly affects females at reproductive age, which has
been associated with hormones, such as prolactin (PRL). Different studies suggest that PRL …