Hippo signaling restricts tumor growth by inhibiting the oncogenic potential of YAP/TAZ‐
TEAD transcriptional complex. Here, we uncover a context‐dependent tumor suppressor …

The Hippo signalling pathway is a master regulator of cell growth, proliferation, and cancer.
The transcriptional coregulators of the Hippo pathway, YAP and TAZ, are central in various …

Despite recent efforts, prostate cancer (PCa) remains one of the most common cancers in
men. Currently, there is no effective treatment for castration-resistant prostate cancer …

The transcriptional co-activator Yes-associated protein 1 (YAP1), a key nuclear effector of
the Hippo pathway, is a potent oncogene, and yet, the interaction between YAP1 and …

Simple Summary Prostate cancer is the most commonly diagnosed cancer in men in the UK,
accounting for the deaths of over 11,000 men per year. A major problem in this disease are …

The Hippo pathway regulates and contributes to several hallmarks of prostate cancer (PCa).
Although the elucidation of YAP function in PCa is in its infancy, emerging studies have shed …

Yes-associated protein (YAP) is an effector of the Hippo tumor suppressor pathway. The
functional significance of YAP in prostate cancer has remained elusive. In this study, we first …

Prostate cancer is a very common malignant disease and a leading cause of death for men
in the Western world. Tumorigenesis and progression of prostate cancer involves multiple …

Hippo signaling restricts tissue growth by inhibiting the transcriptional effector YAP. Here we
uncover a role of Hippo signaling and a tumor suppressor function of YAP in estrogen …

Simple Summary YAP/TAZ are the central effectors of the Hippo pathway and orchestrate
their oncogenic program by binding to TEAD transcriptional factors. Here, we document a …