Genetics of Behçet′ s disease

TI Kaya - Pathology research international, 2012 - Wiley Online Library
Behçet′ s disease (BD) is a systemic inflammatory disorder characterized mainly by
recurrent oral and genital ulcers and eye involvement. Although the pathogenesis remains …

The immunogenetics of Behçet's disease: A comprehensive review

M Takeuchi, DL Kastner, EF Remmers - Journal of autoimmunity, 2015 - Elsevier
Behçet's disease is a chronic multisystem inflammatory disorder characterized mainly by
recurrent oral ulcers, ocular involvement, genital ulcers, and skin lesions, presenting with …

Behcet disease, new insights in disease associations and manifestations: a next-generation sequencing study

M Elfishawi, G Mossallam, DG Augusto… - Clinical & …, 2021 - academic.oup.com
Behçet disease is a multi-system disease associated with human leukocyte antigen (HLA)
class I polymorphism. High-resolution next-generation sequencing (NGS) with haplotype …

Behçet's disease: an overview of etiopathogenesis

P Leccese, E Alpsoy - Frontiers in immunology, 2019 - frontiersin.org
Behçet's disease (BD) is a systemic inflammatory disease with a chronic, relapsing-remitting
course of unknown etiology hallmarked predominantly by mucocutaneous lesions and …

[PDF][PDF] Behcet's disease in Tunisia demographic, clinical and genetic aspects in 260 patients

MH Houman, H Neffati, A Braham… - Clinical and …, 2007 - researchgate.net
Objectives. To analyze demographic, clinical and genetic features of Behçet's disease (BD)
in Tunisia and to'compare them with other ethnic and geographic groups. Methods. Two …

Genetics of Behçet's disease

A Gül, GR Wallace - Behçet Syndrome, 2020 - Springer
Behçet's disease (BD) is a multifactorial disease with a strong genetic background. Higher
frequencies of patients with a positive family history for BD were reported from the Middle …

Global Meta‐Analysis on the Association between Behcet Syndrome and Polymorphisms from the HLA Class I (A, B, and C) and Class II (DRB1, DQB1, and DPB1) …

C Capittini, C Rebuffi, MV Lenti, A Di Sabatino… - Disease …, 2021 - Wiley Online Library
Behcet syndrome (BS) is a multisystemic perivasculitis whose genetic susceptibility is linked
to HLA region. We first meta‐analysed all HLA class I and II genes involved in BS …

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease

EF Remmers, F Cosan, Y Kirino, MJ Ombrello… - Nature …, 2010 - nature.com
Behçet's disease is a genetically complex disease of unknown etiology characterized by
recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed …

Genetic susceptibility to Behcet's disease: role of genes belonging to the MHC region

M Piga, A Mathieu - Rheumatology, 2011 - academic.oup.com
Objective. To review the progress in the field of MHC-related genetic susceptibility to
Behçet's disease (BD). Method. Systematic review of the English literature between 1 …

[PDF][PDF] Genetics of Behçet's disease in Sardinia: two distinct extended HLA haplotypes harbour the B* 51 allele in the normal population and in patients

M Piga, F Paladini, S Lai, G Erre… - Clinical and …, 2012 - clinexprheumatol.org
Objective. To define the contribution of HLA genes and extended HLA haplotypes to the
susceptibility to Behçet's disease (BD) in Sardinia. Methods. Forty-five unrelated Sardinian …