In our recent studies, we identified HLA-DRB1* 0901-binding peptides by affinity-based
selection of a phage random peptide library and showed that two major anchors (WxxS …

When examining anchor residues of a peptide 0405BP2 (1SPGTGAYYVLLN12) that was
eluted from purified HLA-DR4 molecules (DRA DRB1∗ 0405), we found that heptamer …

Three different HLA-DR3-specific peptide binding motifs have been proposed. These motifs
shared a major hydrophobic anchor at the N-terminus, but differed in the C-terminal anchor …

We identified HLA-DRB1∗ 0901-binding peptides by affinity-based selection of a phage
random peptide library using the biotinylated DR9 complex. Analogue peptides with single …

To get further insight into the role of three polymorphic DR residues located in one alpha-
helix of the HLA-DR binding groove, we studied how natural substitutions at positions 67 …

The sequence motif of peptide ligands naturally associated with DR17 has indicated
conserved residues at the relative positions P1-P4-P6-P 8.9 or 10. Eight naturally processed …

In the present study, we describe the definition of a DRB1* 0401 (DR4w4)-specific motif. The
strategy used entailed a three-step process: 1) screening a large set of unrelated peptide …

Peptide binding to class II MHC protein is commonly viewed as a combination of discrete
anchor residue preferences for pockets 1, 4, 6/7, and 9. However, previous studies have …

Abstract Among HLA-DP specificities, HLA-DP4 specificity involves at least two molecules,
HLA-DPA1* 0103/DPB1* 0401 (DP401) and HLA-DPA1* 0103/DPB1* 0402 (DP402), which …

The peptide binding specificities of HLA-DRB1* 0401, DRB1* 0101, and DRB1* 0701 have
been analyzed by the use of large collections of synthetic peptides corresponding to …