Background One of the most important pathogenetic factors involved in the onset of
intradialysis arrhytmias is the alteration in electrolyte concentration, particularly potassium …

The feedback between metabolic acid production and dialytic base gain ensures a neutral
acid–base balance in patients on renal replacement therapy (RRT). Despite acid not …

Background A concentrate for bicarbonate haemodialysis acidified with citrate instead of
acetate has been marketed in recent years. The small amount of citrate used (one-fifth of the …

Introduction Most hemodialysis machines deliver a fixed bicarbonate concentration. Higher
concentrations may improve acidosis, but risk post‐hemodialysis alkalosis, whereas lower …

Clinical studies have suggested that use of bicarbonate-containing substitution and dialysis
fluids during continuous kidney replacement therapy may result in excessive increases in …

This paper proposes an in vitro hemodiafiltration (HDF) model in which the patient is
represented by a 2 L bag of fresh heparinized bovine blood circulated by a 4008H monitor …

Metabolic acidosis occurs when a relative accumulation of plasma anions in excess of
cations reduces plasma pH. Replacement of sodium bicarbonate to patients with sodium …

Background To date, very few studies have been carried out on the associations of pre-and
postdialysis acid-base parameters with mortality in hemodialysis patients. Study Design An …

Several observational studies have reported an association between higher serum
bicarbonate level and high mortality risk in dialysis patients. However, in such studies mere …

Despite major advances in renal replacement therapy over the last 20 years, mild to
moderate metabolic acidosis remains a persistent finding in patients receiving dialysis …