Obesity, a chronic multifaceted disease, predisposes its patients to increased risk of
metabolic disorders such as: diabetes mellitus, cardiovascular diseases, dyslipidemia, etc …

Obesity is a major risk factor for metabolic disease, with white adipose tissue (WAT)
inflammation emerging as a key underlying pathology. Alongside its major role in energy …

Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …

Chronic inflammation of adipose tissue is viewed as a hallmark of obesity and contributes to
the development of type 2 diabetes and cardiovascular disease. According to current …

Adipose tissue (AT) is one of the largest endocrine organs contributing to metabolic
homeostasis. The functional pleiotropism of AT depends on its ability to secrete a large …

Chronic inflammation is a common foundation for the development of many non-
communicable diseases, particularly diabetes, atherosclerosis, and tumors. The activation of …

As Mark Twain said,“Age is an issue of mind over matter. If you don't mind, it doesn't matter.”
But with the demographic shifts in our population, it is time for us to mind and pay more …

Background Therapeutic agents with novel mechanisms of action are needed to combat the
growing epidemic of type 2 diabetes (T2D) and related metabolic syndromes. Liver X …

Publisher Summary This chapter describes how aging is associated with fat tissue
redistribution from subcutaneous to visceral depots. This redistribution is correlated with and …

Type 2 diabetes has traditionally been viewed as a metabolic disorder characterised by
chronic high glucose levels, insulin resistance, and declining insulin secretion from the …