Background: Acute kidney injury (AKI) occurs frequently in the intensive care unit. A primary
cause is renal ischemia/reperfusion (I/R) injury, during which excess reactive oxygen …

Aim To investigate the impact of ischaemic pre‐conditioning (I pre) and post‐conditioning (I
post) on expression of nuclear factor erythroid 2‐related factor 2 (N rf2) gene and its …

Background/Aims: Ischemia/reperfusion (I/R) is the most common cause of acute renal
injury. I/R-induced oxidative stress is involved in the development of acute renal injury …

Postischemic acute kidney injury (AKI) is a common clinical complication and often fatal, with
no effective treatment available. Little is known about the role of leukocytes trapped in renal …

AIMS: Ischemic acute kidney injury (iAKI) in experimental diabetes mellitus (DM) is
associated with a rapid kidney dysfunction more than in non-diabetic rats. We hypothesize …

Background During renal transplantation, the kidney remains without blood flow for a period
of time. The following reperfusion of this ischemic kidney causes functional and structural …

Purpose: We investigated the impact of sex on the protective effect of postconditioning
(POC), a series of brief ischemia-reperfusion (IR) cycles at the reperfusion onset, as a …

Nitric oxide in acute renal failure: NOS versus NOS. This overview provides information on
the pathophysiology of the inducible nitric oxide synthase/nitric oxide (iNOS/NO) system in …

Background Renal ischemia is of great clinical interest because of its role in renal failure
and renal graft rejection. The purpose of this study was to investigate the therapeutic effects …

We investigated the involvement of matrix metalloproteinases (MMPs), tissue inhibitor
(TIMP) and endothelin-1 (ET-1) in the renal damage in spontaneously hypertensive rats …