Systematic research on the physiological and anatomical characteristics of spinal cord
interneurons along with their functional output has evolved for more than one century …

As the nexus between the nervous system and the skeletomuscular system, motoneurons
effect all behavior. As such, motoneuron activity must be well regulated so as to generate …

Key points It is often assumed that central pattern generators, which generate rhythmic
patterns without rhythmic inputs, play a key role in the spinal control of human locomotion …

Networks within our spinal cord generate the basic pattern underlying walking. Over the past
decade, much progress has been made in our understanding of their function in a variety of …

Locomotion is a purposeful, goal‐directed behavior initiated by signals arising from either
volitional processing in the cerebral cortex or emotional processing in the limbic system …

Spinal interneurons are organized into networks that control the activity and output of the
motor system. This review outlines recent progress in defining the rules that govern the …

Human studies in the past three decades have provided us with an emerging understanding
of how cortical and spinal networks collaborate to ensure the vast repertoire of human …

The spinal cord is home to the intrinsic networks for locomotion. An animal in which the
spinal cord has been fully severed from the brain can still produce rhythmic, patterned …

Mapping the expression of transcription factors in the mouse spinal cord has identified ten
progenitor domains, four of which are cardinal classes of molecularly defined, ventrally …

Neuronal networks within the spinal cord directly control rhythmic movements of the
arms/forelimbs and legs/hindlimbs during locomotion in mammals. For an effective …