Expression of Cx26, Cx32 and Cx43 gap junction proteins in normal and neoplastic human tissues

KK Wilgenbus, CJ Kirkpatrick… - … journal of cancer, 1992 - Wiley Online Library
This report concerns the expression of the gapjunction proteins Connexin (Cx) 26, 32 and
43 in different malignant and nonmalignant human tissues. Affinitypurified polyclonal …

Expression of gap junction proteins connexin 26 and connexin 43 in normal human breast and in breast tumours

S Jamieson, JJ Going, R D'Arcy… - The Journal of …, 1998 - Wiley Online Library
Gap junctional intercellular communication (GJIC) has been proposed as a cellular
mechanism for tumour suppression and there is experimental evidence in support of this. If …

Immunochemical characterization of the gap junction protein connexin45 in mouse kidney and transfected human HeLa cells

A Butterweck, U Gergs, C Elfgang, K Willecke… - The Journal of …, 1994 - Springer
Antibodies to the gap junction protein connexin45 (Cx45) were obtained by immunizing
rabbits with fusion protein consisting of glutathione S-transferase and 138 carboxy-terminal …

Characterization of gap junction genes expressed in F9 embryonic carcinoma cells: molecular cloning of mouse connexin31 and-45 cDNAs.

H Hennemann, HJ Schwarz… - European journal of cell …, 1992 - europepmc.org
In an attempt to characterize connexin genes expressed early in mouse development we
screened a cDNA library from mouse F9 embryonic carcinoma cells with mouse connexin37 …

Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43)

RP Huang, Y Fan, MZ Hossain, A Peng, ZL Zeng… - Cancer research, 1998 - AACR
Connexins (cx), structural components of gap junction, are believed to play a role in the
regulation of cell proliferation and suppression of the neoplastic phenotype. We used human …

Localization and function of the connexin 43 gap‐junction protein in normal and various oncogene‐expressing rat liver epithelial cells

AW de Feijter, DF Matesic, RJ Ruch… - … in cooperation with …, 1996 - Wiley Online Library
Clones of rat liver epithelial cells genotypically altered by mutation or by a variety of
oncogenes were analyzed by microinjection‐dye transfer, immunofluorescence confocal …

Ultrastructural localization of gap junction protein connexin 43 in normal human skin, basal cell carcinoma, and squamous cell carcinoma

J Tada, K Hashimoto - Journal of cutaneous pathology, 1997 - Wiley Online Library
The expression and localization of connexin 43 (Cx43) were investigated in normal human
epidermis, pilosebaceous apparatus, basal cell carcinoma, and squamous cell carcinoma …

Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines.

SW Lee, C Tomasetto, D Paul, K Keyomarsi… - The Journal of cell …, 1992 - rupress.org
Subtractive hybridization, selecting for mRNAs expressed in normal human mammary
epithelial cells (NMECs) but not in mammary tumor cell lines (TMECs), led to the cloning of …

Reduced connexin43 expression in high‐grade human brain glioma cells

RP Huang, MZ Hossain, A Sehgal… - Journal of surgical …, 1999 - Wiley Online Library
Abstract Background and Objectives Connexin43 (cx43), a gap junction protein, is
implicated in the suppression of tumor cell growth. Numerous cancer cells show a reduction …

Aberrant expression of gap junction gene in primary human hepatocellular carcinomas: Increased expression of cardiac‐type gap junction gene connexin 43

M Oyamada, VA Krutovskikh, M Mesnil… - Molecular …, 1990 - Wiley Online Library
The expression of connexin 32 (the major liver gap junction protein) and connexin 43 (the
major cardiac gap junction protein) was examined in six surgically removed human …