Environmental pollutants and exosomes: A new paradigm in environmental health and disease

A Javdani-Mallak, I Salahshoori - Science of The Total Environment, 2024 - Elsevier
This study investigates the intricate interplay between environmental pollutants and
exosomes, shedding light on a novel paradigm in environmental health and disease …

Exosomes as mediators of chemical-induced toxicity

D Rokad, H Jin, V Anantharam, A Kanthasamy… - Current environmental …, 2019 - Springer
Abstract Purpose of Review This review provides information regarding how exosomes may
contribute to environmental chemical-induced pathogenesis of chronic diseases. In …

Exosomes in toxicology: relevance to chemical exposure and pathogenesis of environmentally linked diseases

DS Harischandra, S Ghaisas, D Rokad… - Toxicological …, 2017 - academic.oup.com
Chronic exposure to environmental toxins has been known to initiate or aggravate various
neurological disorders, carcinomas and other adverse health effects. Uptake by naïve cells …

In vitro models of exosome biology and toxicology: New frontiers in biomedical research

EC Bowers, AAI Hassanin, KS Ramos - Toxicology in Vitro, 2020 - Elsevier
Exosomes are secreted membrane-bound vesicles containing a cargo of curated nucleic
acids, proteins, and lipids that can alter gene expression in recipient cells. Toxic agents can …

[HTML][HTML] Exosome Cargo in Neurodegenerative Diseases: Leveraging Their Intercellular Communication Capabilities for Biomarker Discovery and Therapeutic …

S Zhang, Y Yang, X Lv, X Zhou, W Zhao, L Meng, S Zhu… - Brain Sciences, 2024 - mdpi.com
The inexorable progression of neurodegenerative diseases (NDs), including Alzheimer's
disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and …

Exosomes: emerging biomarkers unveiling cellular mysteries—a narrative review

IE Umeche, MF Olaniyan - Journal of Bio-X Research, 2023 - mednexus.org
Exosomes have gained recognition as potential diagnostic and prognostic markers due to
their stability and disease-specific cargos. Exosomes, once dismissed as cellular debris, are …

Extracellular vesicles in toxicological studies: key roles in communication between environmental stress and adverse outcomes

Y Qin, L Long, Q Huang - Journal of Applied Toxicology, 2020 - Wiley Online Library
External stressors, especially environmental toxicants can disturb biological homeostasis
and thus lead to adverse health effects. However, there is limited understanding of how cells …

[HTML][HTML] Potential role of exosomes in the pathophysiology, diagnosis, and treatment of hypoxic diseases

P Duan, J Tan, Y Miao, Q Zhang - American Journal of …, 2019 - ncbi.nlm.nih.gov
Exosomes are extracellular vesicles that originate in the endosomal system. They perform
important functions for cell-to-cell communication by transferring bioactive cargoes to …

Enabling metabolomics based biomarker discovery studies using molecular phenotyping of exosome-like vesicles

T Altadill, I Campoy, L Lanau, K Gill, M Rigau… - PLoS …, 2016 - journals.plos.org
Identification of sensitive and specific biomarkers with clinical and translational utility will
require smart experimental strategies that would augment expanding the breadth and depth …

Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA

M Eldh, K Ekström, H Valadi, M Sjöstrand, B Olsson… - PloS one, 2010 - journals.plos.org
Background Exosomes are small extracellular nanovesicles of endocytic origin that mediate
different signals between cells, by surface interactions and by shuttling functional RNA from …