Optically active 1-phenylethanol and its derivatives are versatile chiral precursors for many
pharmaceuticals. The increasing market demand of enantiopure alcohols calls for …

The biocatalytic anti-Prelog stereoselective reduction of ethyl acetoacetate (EAA) to ethyl (R)-
3-hydroxybutyrate {(R)-EHB} was successfully conducted in the aqueous system using …

A practical and highly efficient biocatalytic synthesis of optically active (R)‐4‐
fluorophenylethan‐1‐ol has been developed based on reduction of the corresponding 4 …

Abstract Whole-cell reduction of (2, 5)-hexanedione to yield highly enantiopure (5 R)-
hydroxyhexane-2-one (enantiomeric excess> 99%) with Lactobacillus kefiri DSM 20587 was …

The enantioselective reduction of acetophenone analogues catalyzed by carrot and celeriac
was performed in moderate conversions and excellent enantiomeric excesses. The steric …

Abstract Reduction of bicyclo [2.2. 2] octane-2, 6-dione to (1R, 4S, 6S)-6-hydroxy-bicyclo
[2.2. 2] octane-2-one by whole cells of Saccharomyces cerevisiae was improved using an …

The enantioselective bioreduction of alpha-substituted-acetophenones 1, 2 was carried out
with cells of fungi to give the corresponding chiral alcohols in good yield and high …

The asymmetric bioreduction of ethyl 3-halo-2-oxo-4-phenylbutanoate was studied for
several microorganisms and especially for Saccharomyces cerevisiae. The highest chemical …

Asymmetric synthesis of chiral β-hydroxy esters, the key building blocks for many functional
materials, is currently of great interest. In this study, the biocatalytic anti-Prelog reduction of …

Rhodotorula sp. LSL, isolated from a local landfarming was able to catalyze the reduction of
prochiral arylketones into sec-alcohols with excellent Prelog stereoselectivity (ee> 99%) …