Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), remains the
leading cause of death worldwide from a single infectious pathogen. Mtb is a paradigmatic …

Mycobacterium tuberculosis (MTB) is one of the most successful pathogens in human history
and remains a global health challenge. MTB has evolved a plethora of strategies to evade …

Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …

T cells play a cardinal role in imparting protection against Mycobacterium tuberculosis (Mtb).
However, ample time is required before T-cells are able to evoke efficient effector responses …

Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

Tuberculosis (TB) caused by the intracellular pathogen, Mycobacterium tuberculosis (Mtb),
claims more than 1.5 million lives worldwide annually. Despite promulgation of multipronged …

Macrophages play an essential role in the immune system by ingesting and degrading
invading pathogens, initiating an inflammatory response and instructing adaptive immune …

Cells in homeostasis metabolize glucose mainly through the tricarboxylic acid cycle and
oxidative phosphorylation, while activated cells switch their basal metabolism to aerobic …

The major innate immune cell types involved in tuberculosis (TB) infection are
macrophages, dendritic cells (DCs), neutrophils and natural killer (NK) cells. These immune …

Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …