Marfan syndrome (MFS) is a connective tissue disorder that is often associated with the
fibrillin-1 (Fbn1) gene mutation and characterized by cardiovascular alterations …

Marfan syndrome (MFS) is characterized by the formation of ascending aortic aneurysms
resulting from altered assembly of extracellular matrix fibrillin-containing microfibrils and …

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1
gene, which encodes fibrillin-1, a protein essential for the formation and stabilization of …

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in fibrillin-1
(Fbn1). Although aortic rupture is the major cause of mortality in MFS, patients also …

Background and purpose: Aortic complications account for the major mortality in Marfan
syndrome (MFS), a connective tissue disorder caused by mutations in FBN1 encoding …

Marfan syndrome (MS) is of the most common connective tissue disorders. Although most
patients have mutations in the fibrillin-1 gene (FBN1) and more than 1,700 mutations have …

Aims Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the
Fibrillin-1 gene. It is associated with formation of thoracic aortic aneurysms that can …

Marfan syndrome (MFS) is a connective tissue disorder that results in aortic root aneurysm
formation. Reactive oxygen species (ROS) seem to play a role in aortic wall remodelling in …

Abstract In individuals with Marfan Syndrome (MFS), fibrillin-1 gene (FBN1) mutations can
lead to vascular wall weakening and dysfunction. The experimental mouse model of MFS …

Background: Marfan syndrome (MFS), an inherited disorder of connective tissue
characterized by abnormalities in the skeletal, ocular, and cardiovascular systems, is caused …