The anti-inflammatory and immunological properties of GLP-1 Receptor Agonists

G Bendotti, L Montefusco, ME Lunati, V Usuelli… - Pharmacological …, 2022 - Elsevier
In the last few years, a great interest has emerged in investigating the pleiotropic effects of
Glucagon Like Peptide-1 Receptor Agonists (GLP-1RAs). While GLP-1RAs ability to lower …

Anti-inflammatory role of glucagon-like peptide 1 receptor agonists and its clinical implications

SH Alharbi - Therapeutic Advances in Endocrinology and …, 2024 - journals.sagepub.com
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have emerged as promising
therapeutic agents with potent anti-inflammatory properties and diverse clinical implications …

Cardiovascular effects of glucagon-like peptide 1 receptor agonists: from mechanistic studies in humans to clinical outcomes

VD Heuvelman, DH Van Raalte… - Cardiovascular …, 2020 - academic.oup.com
Type 2 diabetes mellitus (T2DM) is currently one of the most prevalent diseases, with as
many as 415 million patients worldwide. T2DM is characterized by elevated blood glucose …

Glucagon‐like peptide‐1 receptor agonists improve biomarkers of inflammation and oxidative stress: a systematic review and meta‐analysis of randomised controlled …

JJH Bray, H Foster‐Davies, A Salem… - Diabetes, Obesity …, 2021 - Wiley Online Library
Aim To conduct a meta‐analysis and systematic review to examine the effects of glucagon‐
like peptide‐1 receptor agonists (GLP‐1RAs) on clinical biomarkers of inflammation and …

GLP-1 receptor agonist as a modulator of innate immunity

J Chen, A Mei, Y Wei, C Li, H Qian, X Min… - Frontiers in …, 2022 - frontiersin.org
Glucagon-like peptide-1 (GLP-1) is a 30-amino acid hormone secreted by L cells in the
distal ileum, colon, and pancreatic α cells, which participates in blood sugar regulation by …

Anti‐inflammatory effects of GLP‐1‐based therapies beyond glucose control

YS Lee, HS Jun - Mediators of inflammation, 2016 - Wiley Online Library
Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone mainly secreted from intestinal L
cells in response to nutrient ingestion. GLP‐1 has beneficial effects for glucose homeostasis …

[HTML][HTML] GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential

X Ma, Z Liu, I Ilyas, PJ Little, D Kamato… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) is closely associated with cardiovascular diseases (CVD),
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …

[HTML][HTML] GLP-1 receptor agonists: beyond their pancreatic effects

X Zhao, M Wang, Z Wen, Z Lu, L Cui, C Fu… - Frontiers in …, 2021 - frontiersin.org
Glucagon like peptide-1 (GLP-1) is an incretin secretory molecule. GLP-1 receptor agonists
(GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their …

The cardiovascular biology of glucagon-like peptide-1

DJ Drucker - Cell metabolism, 2016 - cell.com
Glucagon-like peptide-1, produced predominantly in enteroendocrine cells, controls glucose
metabolism and energy homeostasis through regulation of islet hormone secretion …

Glucagon and glucagon-like peptide-1 as novel anti-inflammatory and immunomodulatory compounds

DBR Insuela, VF Carvalho - European journal of pharmacology, 2017 - Elsevier
Glucagon and glucagon-like peptide-1 (GLP-1) are polypeptide hormones that are produced
by pancreatic α-cells and the intestine, respectively, whose main function is to control …