[HTML][HTML] A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and …

MF Mohamed, A Brezden, H Mohammad… - Scientific Reports, 2017 - nature.com
Antimicrobial peptides (AMPs) represent a promising therapeutic alternative for the
treatment of antibiotic-resistant bacterial infections. The present study investigates the …

[HTML][HTML] Synergistic and antibiofilm activity of the antimicrobial peptide P5 against carbapenem-resistant Pseudomonas aeruginosa

M Martinez, S Gonçalves, MR Felício… - … et Biophysica Acta (BBA …, 2019 - Elsevier
In the search for new antimicrobial molecules, antimicrobial peptides (AMPs) offer a viable
alternative to conventional antibiotics, as they physically disrupt the bacterial membranes …

[HTML][HTML] Novel D-form of hybrid peptide (D-AP19) rapidly kills Acinetobacter baumannii while tolerating proteolytic enzymes

P Jariyarattanarach, N Klubthawee, M Wongchai… - Scientific Reports, 2022 - nature.com
Antimicrobial peptides (AMPs) are being developed as potent alternative treatments to
conventional antibiotics which are unlikely to induce bacterial resistance. They can be …

[HTML][HTML] In vitro properties of designed antimicrobial peptides that exhibit potent antipneumococcal activity and produces synergism in combination with penicillin

CF Le, MYM Yusof, H Hassan, SD Sekaran - Scientific reports, 2015 - nature.com
Antimicrobial peptides (AMPs) represent a promising class of novel antimicrobial agents
owing to their potent antimicrobial activity. In this study, two lead peptides from unrelated …

[HTML][HTML] Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78

C Monteiro, M Fernandes, M Pinheiro, S Maia… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Antimicrobial peptides (AMPs) are a class of broad-spectrum antibiotics known by their
ability to disrupt bacterial membranes and their low tendency to induce bacterial resistance …

[HTML][HTML] Antimicrobial activity of α-peptide/β-peptoid lysine-based peptidomimetics against colistin-resistant pseudomonas aeruginosa isolated from cystic fibrosis …

N Molchanova, H Wang, PR Hansen, N Høiby… - Frontiers in …, 2019 - frontiersin.org
Pseudomonas aeruginosa infection is a predominant cause of morbidity and mortality in
patients with cystic fibrosis infection and with a compromised immune system. Emergence of …

[HTML][HTML] Hydrophilic/hydrophobic characters of antimicrobial peptides derived from animals and their effects on multidrug resistant clinical isolates

LIU Cun-Bao, S Bin, BAI Hong-Mei, T Jing… - Zoological …, 2015 - ncbi.nlm.nih.gov
Multidrug resistant (MDR) pathogen infections are serious threats to hospitalized patients
because of the limited therapeutic options. A novel group of antibiotic candidates …

New antimicrobial peptides with repeating unit against multidrug-resistant bacteria

C Zhong, F Zhang, J Yao, Y Zhu, N Zhu… - ACS Infectious …, 2021 - ACS Publications
With the aim of tackling the increasingly serious antimicrobial resistance and improving the
clinical potential of AMPs, a facile de novo strategy was adopted in this study, and a series of …

[HTML][HTML] Amphipathic peptide antibiotics with potent activity against multidrug-resistant pathogens

J Shi, C Chen, D Wang, Z Tong, Z Wang, Y Liu - Pharmaceutics, 2021 - mdpi.com
The emergence and prevalence of multidrug-resistant (MDR) bacteria have posed a serious
threat to public health. Of particular concern are methicillin-resistant Staphylococcus aureus …

[HTML][HTML] “Specificity determinants” improve therapeutic indices of two antimicrobial peptides piscidin 1 and dermaseptin S4 against the Gram-negative pathogens …

Z Jiang, AI Vasil, ML Vasil, RS Hodges - Pharmaceuticals, 2014 - mdpi.com
A new class of antimicrobial agents with lower rates of resistance and different targets is
urgently needed because of the rapidly increasing resistance to classical antibiotics …