The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Pseudomonas aeruginosa infections represent a serious threat to worldwide health. Proline-
rich antimicrobial peptides (PR-AMPs), a particular group of peptide antibiotics, have …

Antimicrobial peptides (AMPs) are promising alternatives to classical antibiotics for the
treatment of drug-resistant infections. Due to their versatility and unlimited sequence space …

In the present study, the 26-residue peptide sequence Ac-
KWKSFLKTFKSAVKTVLHTALKAISS-amide (V 681) was utilized as the framework to study …

Antimicrobial peptides are ubiquitous in multicellular organisms and have served as
defense mechanisms for their successful evolution and throughout their life cycle. These …

The emergence of carbapenem-resistant Acinetobacter baumannii and Pseudomonas
aeruginosa raises fears of untreatable infections and poses the greatest health threats …

Rapid antimicrobial action is an important advantage of antimicrobial peptides (AMPs) over
antibiotics, which is also a reason for AMPs being less likely to induce bacterial resistance …

Introduction: As the development of new antimicrobial agents faces a historical decline, the
issue of bacterial drug resistance has become a serious dilemma that threatens the human …

We previously reported a series of de novo engineered cationic antibiotic peptides (eCAPs)
consisting exclusively of arginine and tryptophan (WR) that display potent activity against …

Antimicrobial peptides (AMPs) and their synthetic mimics have received recent interest as
new alternatives to traditional antibiotics in attempts to overcome the rise of antibiotic …