Cationic amphiphilic peptides: Synthetic antimicrobial agents inspired by nature
R Kundu - ChemMedChem, 2020 - Wiley Online Library
Antimicrobial peptides are ubiquitous in multicellular organisms and have served as
defense mechanisms for their successful evolution and throughout their life cycle. These …
defense mechanisms for their successful evolution and throughout their life cycle. These …
The mechanism of killing by the proline-rich peptide Bac7 (1–35) against clinical strains of Pseudomonas aeruginosa differs from that against other Gram-negative …
G Runti, M Benincasa, G Giuffrida… - Antimicrobial Agents …, 2017 - Am Soc Microbiol
Pseudomonas aeruginosa infections represent a serious threat to worldwide health. Proline-
rich antimicrobial peptides (PR-AMPs), a particular group of peptide antibiotics, have …
rich antimicrobial peptides (PR-AMPs), a particular group of peptide antibiotics, have …
The antimicrobial peptide ZY4 combats multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii infection
J Mwangi, Y Yin, G Wang, M Yang… - Proceedings of the …, 2019 - National Acad Sciences
The emergence of carbapenem-resistant Acinetobacter baumannii and Pseudomonas
aeruginosa raises fears of untreatable infections and poses the greatest health threats …
aeruginosa raises fears of untreatable infections and poses the greatest health threats …
Proline hinged amphipathic α-helical peptide sensitizes gram-negative bacteria to various gram-positive antibiotics
S Hyun, Y Choi, D Jo, S Choo, TW Park… - Journal of Medicinal …, 2020 - ACS Publications
Gram-negative bacteria are becoming resistant to almost all currently available antibiotics.
Systemically designed antimicrobial peptides (AMPs) are attractive agents to enhance the …
Systemically designed antimicrobial peptides (AMPs) are attractive agents to enhance the …
Antimicrobial peptides under clinical investigation
HB Koo, J Seo - Peptide Science, 2019 - Wiley Online Library
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …
Antimicrobial peptides (AMPs): peptide structure and mode of action
YK Park, KS Hahm - BMB Reports, 2005 - koreascience.kr
Antimicrobial peptides (AMPs) have been isolated and characterized from tissues and
organisms representing virtually every kingdom and phylum. Their amino acid composition …
organisms representing virtually every kingdom and phylum. Their amino acid composition …
Alpha-helical cationic antimicrobial peptides: relationships of structure and function
Y Huang, J Huang, Y Chen - Protein & cell, 2010 - Springer
Antimicrobial peptides (AMPs), with their extraordinary properties, such as broad-spectrum
activity, rapid action and difficult development of resistance, have become promising …
activity, rapid action and difficult development of resistance, have become promising …
The pharmacophore of short cationic antibacterial peptides
MB Strøm, BE Haug, ML Skar, W Stensen… - Journal of medicinal …, 2003 - ACS Publications
Cationic antibacterial peptides have been proclaimed as new drugs against multiresistant
bacteria. Their limited success so far is partially due to the size of the peptides, which gives …
bacteria. Their limited success so far is partially due to the size of the peptides, which gives …
Antimicrobial peptides and their analogs: searching for new potential therapeutics
K Midura-Nowaczek… - Perspectives in medicinal …, 2014 - journals.sagepub.com
Antimicrobial peptides (AMPs) are an essential part of innate immunity. These compounds
have been considered as potential therapeutics because of their broad-spectrum activities …
have been considered as potential therapeutics because of their broad-spectrum activities …
Development of Bactericidal Peptides against Multidrug-Resistant Acinetobacter baumannii with Enhanced Stability and Low Toxicity
PK Hazam, CC Cheng, CY Hsieh, WC Lin… - International Journal of …, 2022 - mdpi.com
Pathogenic superbugs are the root cause of untreatable complex infections with limited or
no treatment options. These infections are becoming more common as clinical antibiotics …
no treatment options. These infections are becoming more common as clinical antibiotics …