Pregnant women and their fetuses are orphan populations with respect to the safety and
efficacy of drugs. Physiological and absorption, distribution, metabolism, and excretion …

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dIow lhe: dllttuon or ellanl". Increased Yolume ordlsmbul1on (Vd) can Iol'>'er the: pta $ ma …

Essentially all drugs taken by a pregnant woman reach her fetus. The consequences of fetal
drug exposure may be inconsequential, disastrous, or, in most cases, unknown …

Effective and safe drug administration should be based on knowledge that integrates the
evolving physiological characteristics of the individual patient who will receive the drug with …

The use of drugs in pregnant and lactating women requires a thorough understanding of the
unique interactions between the mother, fetus/infant, and the pharmacologic agents that are …

The changes in pregnancy that affect drug absorption, distribution, metabolism, and
elimination can be broken down into two categories:(1) physiologic changes in pregnancy …

Drug therapy in pregnancy may cause anxiety to both physicians and patients due to
uncertainty regarding dosing and safety. Nevertheless, the need for medication is high given …

Drug usage in the pregnant or lactating patient poses a complex problem for the emergency
physician. The altered maternal physiology needs to be understood, and the potential …

Prescription drug use is prevalent during the pediatric period and increases with age.[1]
Very few individuals survive their life expectancy without receiving chronic medications or …