Karyotype and age in acute myeloid leukemia.: Are they linked?
AV Moorman, E Roman, EV Willett, GJ Dovey… - Cancer genetics and …, 2001 - Elsevier
A novel hierarchical cytogenetic classification for acute myeloid leukemia (AML) has been
developed. Patients with successful cytogenetics and a diagnosis of AML were categorized …
developed. Patients with successful cytogenetics and a diagnosis of AML were categorized …
Impact of genetic features on treatment decisions in AML
H Döhner, VI Gaidzik - Hematology 2010, the American Society …, 2011 - ashpublications.org
In recent years, research in molecular genetics has been instrumental in deciphering the
molecular pathogenesis of acute myeloid leukemia (AML). With the advent of the novel …
molecular pathogenesis of acute myeloid leukemia (AML). With the advent of the novel …
[HTML][HTML] The clinical impact of the molecular landscape of acute myeloid leukemia
S Kayser, MJ Levis - Haematologica, 2023 - ncbi.nlm.nih.gov
Research into the underlying pathogenic mechanisms of acute myeloid leukemia (AML) has
led to remarkable advances in our understanding of the disease. Mutations now allow us to …
led to remarkable advances in our understanding of the disease. Mutations now allow us to …
ALL-1 Gene Rearrangements in Acute Myeloid Leukemia: Association with M4–M5 French-American-British Classification Subtypes and Young Age
G Cimino, MC Rapanotti, L Elia, A Biondi, M Fizzotti… - Cancer research, 1995 - AACR
We have analyzed by Southern blotting the ALL-1 (MLL, HRX, Hrtx 1) gene configuration in
a series of 126 patients with acute myeloid leukemia (AML) representative of all ages and …
a series of 126 patients with acute myeloid leukemia (AML) representative of all ages and …
Advances in understanding the biology and genetics of acute myelocytic leukemia
SB McKenzie - American Society for Clinical Laboratory Science, 2005 - clsjournal.ascls.org
Acute myelocytic leukemia (AML) is a malignant neoplasm of hematopoietic cells
characterized by an abnormal proliferation of myeloid precursor cells, decreased rate of self …
characterized by an abnormal proliferation of myeloid precursor cells, decreased rate of self …
Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia
WY Cheng, JF Li, YM Zhu, XJ Lin… - Proceedings of the …, 2022 - National Acad Sciences
The current classification of acute myeloid leukemia (AML) relies largely on genomic
alterations. Robust identification of clinically and biologically relevant molecular subtypes …
alterations. Robust identification of clinically and biologically relevant molecular subtypes …
[HTML][HTML] Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and-M2 through boutique microarrays, real-time PCR and …
L Handschuh, M Kaźmierczak… - International …, 2018 - spandidos-publications.com
Acute myeloid leukemia (AML) is the most common and severe form of acute leukemia
diagnosed in adults. Owing to its heterogeneity, AML is divided into classes associated with …
diagnosed in adults. Owing to its heterogeneity, AML is divided into classes associated with …