Mutations in α-tubulin promote basal body maturation and flagellar assembly in the absence of δ-tubulin

S Fromherz, TH Giddings Jr… - Journal of cell …, 2004 - journals.biologists.com
We have isolated suppressors of the deletion allele of δ-tubulin, uni3-1, in the biflagellate
green alga Chlamydomonas reinhardtii. The deletion of δ-tubulin produces cells that …

Microtubule assembly in cold-adapted organisms: functional properties and structural adaptations of tubulins from antarctic fishes

HW Detrich III - Comparative Biochemistry and Physiology Part A …, 1997 - Elsevier
Fishes native to the coastal waters of the Antarctic have adapted to habitat and body
temperatures in the range− 1.8 to+ 2° C. Their cytoplasmic microtubules, unlike those of …

[HTML][HTML] Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins

M Ichikawa, D Liu, PL Kastritis, K Basu, TC Hsu… - Nature …, 2017 - nature.com
Cilia are ubiquitous, hair-like appendages found in eukaryotic cells that carry out functions of
cell motility and sensory reception. Cilia contain an intriguing cytoskeletal structure, termed …

Microtubules

P Dráber, E Dráberová - Cytoskeleton and human disease, 2012 - Springer
Microtubules, assembled from heterodimers of α-and β-tubulin, are hollow tubes of about 25
nm in diameter, participating in essential cellular functions such as maintenance of cell …

A new function for the γ-tubulin ring complex as a microtubule minus-end cap

C Wiese, Y Zheng - Nature cell biology, 2000 - nature.com
Microtubule nucleation from centrosomes involves a lockwasher-shaped protein complex
containing γ-tubulin, named the γ-tubulin ring complex (γTuRC). Here we investigate the …

Identification of intrinsic dimer and overexpressed monomeric forms of γ-tubulin in Sf9 cells infected with baculovirus containing the Chlamydomonas γ-tubulin …

A Vassilev, M Kimble, CD Silflow… - Journal of cell …, 1995 - journals.biologists.com
ABSTRACT A new member of the tubulin superfamily, γ-tubulin, is localized at microtubule-
organizing centers (MTOCs) in a variety of organisms. Chlamydomonas cDNA coding for the …

[PDF][PDF] Tubulin and microtubules

LA Amos - Nature Encyclopedia of Life Sciences, 2005 - researchgate.net
The protein tubulin is the principal constituent of microtubules, whose dynamic behaviour
allows them to perform a vital role in various forms of cell motility. Found in almost all types …

γ-Tubulin in differentiated cell types: localization in the vicinity of basal bodies in retinal photoreceptors and ciliated epithelia

V Muresan, HC Joshi, JC Besharse - Journal of Cell Science, 1993 - journals.biologists.com
ABSTRACT γ-Tubulin, a newly discovered member of the tubulin superfamily required for
microtubule nucleation, is associated with the centrosome (s) throughout the vertebrate cell …

[HTML][HTML] The core of the mammalian centriole contains γ-tubulin

SD Fuller, BE Gowen, S Reinsch, A Sawyer, B Buendia… - Current Biology, 1995 - cell.com
Background: The microtubule network, upon which transport occurs in higher cells, is formed
by the polymerization of α and β tubulin. The third major tubulin isoform, γ tubulin, is …

[HTML][HTML] Microtubules in microorganisms: how tubulin isotypes contribute to diverse cytoskeletal functions

A Bera, ML Gupta Jr - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The cellular functions of the microtubule (MT) cytoskeleton range from relatively simple to
amazingly complex. Assembled from tubulin, a heterodimeric protein with α-and β-tubulin …