Granulocyte colony-stimulating factor preferentially stimulates proliferation of monosomy 7 cells bearing the isoform IV receptor
EM Sloand, ASM Yong… - Proceedings of the …, 2006 - National Acad Sciences
Granulocyte colony-stimulating factor (GCSF) administration has been linked to the
development of monosomy 7 in severe congenital neutropenia and aplastic anemia. We …
development of monosomy 7 in severe congenital neutropenia and aplastic anemia. We …
Inhibition of granulocyte colony-stimulating factor–mediated myeloid maturation by low level expression of the differentiation-defective class IV granulocyte colony …
SM White, MH Alarcon… - Blood, The Journal of the …, 2000 - ashpublications.org
In acute myeloid leukemia (AML), granulocyte colony-stimulating factor receptor (G-CSFR)
proliferative and maturational signaling pathways are uncoupled. Seven human G-CSFR …
proliferative and maturational signaling pathways are uncoupled. Seven human G-CSFR …
Expression and functional analysis of granulocyte colony‐stimulating factor receptors on CD34++ cells in patients with myelodysplastic syndrome (MDS) and MDS …
TA Sultana, H Harada, K Ito, H Tanaka… - British journal of …, 2003 - Wiley Online Library
CD34++ cells from 45 patients with myelodysplastic syndrome (MDS) and MDS‐acute
myeloid leukaemia (MDS‐AML) were observed by flow cytometry for the expression of …
myeloid leukaemia (MDS‐AML) were observed by flow cytometry for the expression of …
Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition
HM Mehta, M Futami, T Glaubach, DW Lee… - Leukemia, 2014 - nature.com
Granulocyte colony-stimulating factor (GCSF) drives the production of myeloid progenitor
and precursor cells toward neutrophils via the GCSF receptor (GCSFR, gene name CSF3R) …
and precursor cells toward neutrophils via the GCSF receptor (GCSFR, gene name CSF3R) …
A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome
A Wölfler, SJ Erkeland, C Bodner, M Valkhof… - Blood, 2005 - ashpublications.org
The granulocyte colony-stimulating factor receptor (G-CSF-R) transmits signals for
proliferation and differentiation of myeloid progenitor cells. Here we report on the …
proliferation and differentiation of myeloid progenitor cells. Here we report on the …
Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells
AC Ward, L Smith, JP De Koning, Y Van Aesch… - Journal of Biological …, 1999 - ASBMB
Granulocyte colony-stimulating factor (G-CSF) regulates neutrophil production through
activation of its cognate receptor, the G-CSF-R. Previous studies with deletion mutants have …
activation of its cognate receptor, the G-CSF-R. Previous studies with deletion mutants have …
Increased expression of the differentiation-defective granulocyte colony-stimulating factor receptor mRNA isoform in acute myelogenous leukemia
SM White, ED Ball, WC Ehmann, AS Rao, DJ Tweardy - Leukemia, 1998 - nature.com
Granulocyte colony-stimulating factor (G-CSF) critically affects all stages of granulopoiesis
by activating a signaling cascade initiated by dimerization of its receptor (G-CSFR). Five …
by activating a signaling cascade initiated by dimerization of its receptor (G-CSFR). Five …
A point mutation in the granulocyte colony-stimulating factor receptor (G-CSF-R) gene in a case of acute myeloid leukemia results in the overexpression of a novel G …
F Dong, M van Paassen, C van Buitenen, LH Hoefsloot… - 1995 - ashpublications.org
A novel human granulocyte colony-stimulating factor (G-CSF) receptor isoform, designated
SD, has been identified in which the distal C-terminal cytoplasmic region, previously shown …
SD, has been identified in which the distal C-terminal cytoplasmic region, previously shown …
Endogenous serum levels and surface receptor expression of GM-CSF and IL-3 in patients with myelodysplastic syndromes
H Zwierzina, S Schöllenberger, M Herold, F Schmalzl… - Leukemia research, 1992 - Elsevier
The majority of patients suffering from myelodysplastic syndromes (MDS) die of
complications due to cytopenia. Clinical trials have demonstrated that in an essential …
complications due to cytopenia. Clinical trials have demonstrated that in an essential …
Transformation of congenital neutropenia into monosomy 7 and acute nonlymphoblastic leukemia in a child treated with granulocyte colony-stimulating factor
ME Weinblatt, P Scimeca, A James-Herry… - The Journal of …, 1995 - Elsevier
A cytogenetically normal infant with Kostmann syndrome (severe congenital
granulocytopenia) was treated with granulocyte colony-stimulating factor, which resulted in a …
granulocytopenia) was treated with granulocyte colony-stimulating factor, which resulted in a …