Mortality in schizophrenia-spectrum disorders: recent advances in understanding and management

V Peritogiannis, A Ninou, M Samakouri - Healthcare, 2022 - mdpi.com
Schizophrenia is a life-shortening disease and life expectancy in patients may be 15–20
years shorter than in the general population, with increasing longevity gap over time …

Mortality and the relationship of somatic comorbidities to mortality in schizophrenia. A nationwide matched-cohort study

I Bitter, P Czobor, A Borsi, L Fehér, BZ Nagy… - European …, 2017 - cambridge.org
Aim: We conducted a matched-cohort study to assess mortality in schizophrenia and the
relationship of mortality with comorbid somatic conditions and suicide attempts. Method: A …

Clozapine and long-term mortality risk in patients with schizophrenia: a systematic review and meta-analysis of studies lasting 1.1–12.5 years

JM Vermeulen, G van Rooijen… - Schizophrenia …, 2019 - academic.oup.com
Introduction Patients with schizophrenia have an elevated mortality risk compared to the
general population, with cardiovascular-related deaths being the leading cause. The role of …

Premature mortality among adults with schizophrenia in the United States

M Olfson, T Gerhard, C Huang, S Crystal… - JAMA …, 2015 - jamanetwork.com
Importance Although adults with schizophrenia have a significantly increased risk of
premature mortality, sample size limitations of previous research have hindered the …

20‐year follow‐up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia …

H Taipale, A Tanskanen, J Mehtälä… - World …, 2020 - Wiley Online Library
Antipsychotics are effective in preventing relapses of schizophrenia, but it is generally
believed that their long‐term use is harmful for patients' physical well‐being. However, there …

[PDF][PDF] Balancing therapeutic safety and efficacy to improve clinical and economic outcomes in schizophrenia: a clinical overview

DC Javitt - Am J Manag Care, 2014 - ajmc.s3.amazonaws.com
Affecting up to 1% of the global population, schizophrenia is a chronic, disabling psychiatric
disorder that has profound effects on patients, families, and caretakers due to its tremendous …

How can we improve the care of patients with schizophrenia in the real-world? A population-based cohort study of 456,003 patients

G Fond, B Falissard, P Nuss, C Collin, S Duret… - Molecular …, 2023 - nature.com
An important step to improve outcomes for patients with schizophrenia is to understand
treatment patterns in routine practice. The aim of the current study was to describe the long …

Do antipsychotic medications reduce or increase mortality in schizophrenia? A critical appraisal of the FIN-11 study

M De Hert, CU Correll, D Cohen - Schizophrenia research, 2010 - Elsevier
Compared to the general population, people with schizophrenia are at risk of dying
prematurely due to suicide and due to different somatic illnesses. The potential role of …

Schizophrenia as a risk factor for cardiovascular and metabolic health outcomes: a comparative risk assessment

S Ali, D Santomauro, AJ Ferrari… - … and Psychiatric Sciences, 2023 - cambridge.org
AimsCardiometabolic diseases are responsible for the majority of premature deaths in
people with schizophrenia. This study aimed to quantify the fatal burden of ischaemic heart …

Schizophrenia treatment with second-generation antipsychotics: a multi-country comparison of the costs of cardiovascular and metabolic adverse events and weight …

B Kearns, K Cooper, A Cantrell… - … Disease and Treatment, 2021 - Taylor & Francis
Purpose Cardiovascular and metabolic adverse events are costly to treat, and their
incidence is increased amongst people with schizophrenia, with different rates observed for …