Evolving from bioinformatics in-the-small to bioinformatics in-the-large

DS Parker, MM Gorlick, CJ Lee - OMICS A Journal of Integrative …, 2003 - liebertpub.com
We argue the significance of a fundamental shift in bioinformatics, from in-the-small to in-the-
large. Adopting a large-scale perspective is a way to manage the problems endemic to the …

[HTML][HTML] Community development, implementation, and assessment of a NIBLSE bioinformatics sequence similarity learning resource

AJ Kleinschmit, EF Ryder, JL Kerby, B Murdoch… - Plos one, 2021 - journals.plos.org
As powerful computational tools and 'big data'transform the biological sciences,
bioinformatics training is becoming necessary to prepare the next generation of life …

Ten recommendations for creating usable bioinformatics command line software

T Seemann - GigaScience, 2013 - academic.oup.com
Bioinformatics software varies greatly in quality. In terms of usability, the command line
interface is the first experience a user will have of a tool. Unfortunately, this is often also the …

Integration and querying of genomic and proteomic semantic annotations for biomedical knowledge extraction

M Masseroli, A Canakoglu… - IEEE/ACM Transactions on …, 2015 - ieeexplore.ieee.org
Understanding complex biological phenomena involves answering complex biomedical
questions on multiple biomolecular information simultaneously, which are expressed …

BioGrakn: a knowledge graph-based semantic database for biomedical sciences

A Messina, H Pribadi, J Stichbury, M Bucci… - Complex, Intelligent, and …, 2018 - Springer
The proliferation of biological research data generated and shared openly online is of huge
benefit to the scientific community, but there are often significant challenges to overcome …

[HTML][HTML] Extending the evaluation of Genia Event task toward knowledge base construction and comparison to Gene Regulation Ontology task

JD Kim, J Kim, X Han, D Rebholz-Schuhmann - BMC bioinformatics, 2015 - Springer
Background The third edition of the BioNLP Shared Task was held with the grand theme"
knowledge base construction (KB)". The Genia Event (GE) task was re-designed and …

On the evolving portfolio of community-standards and data sharing policies: turning challenges into new opportunities

SA Sansone, P Rocca-Serra - GigaScience, 2012 - academic.oup.com
There are thousands of biology databases with hundreds of terminologies, reporting
guidelines, representations models, and exchange formats to help annotate, report, and …

Design, implementation and updating of knowledge bases

S Hunter, R Apweiler, MJ Martin - … ‐Based Bioinformatics: From …, 2010 - Wiley Online Library
A clear message emanates from the major bioinformatics infrastructure institutes and
initiatives: the development and maintenance of biological knowledge bases is core to their …

Closing the computational biology 'knowledge gap': Spanish Wikipedia as a case study

N Sélem-Mojica, T Karakulak, A Anjum… - …, 2024 - academic.oup.com
Motivation Wikipedia is a vital open educational resource in computational biology. The
quality of computational biology coverage in English-language Wikipedia has improved …

[HTML][HTML] Knowledge Base Commons (KBCommons) v1. 1: a universal framework for multi-omics data integration and biological discoveries

S Zeng, Z Lyu, SRK Narisetti, D Xu, T Joshi - BMC genomics, 2019 - Springer
Abstract Background Knowledge Base Commons (KBCommons) v1. 1 is a universal and all-
inclusive web-based framework providing generic functionalities for storing, sharing …