Disease and accompanying inflammation are uncommon outcomes of viral infection in
humans. Clinical inflammation occurs if steady-state cell-intrinsic and leukocytic immunity to …

The immune system protects from infections primarily by detecting and eliminating the
invading pathogens; however, the host organism can also protect itself from infectious …

Much progress has been made in the identification of specific human gene variants that
contribute to enhanced susceptibility or resistance to viral diseases. Herein we review …

Viral infectious diseases signify an essential portion of global public health concern with
millions of deaths annually. Viruses produce disease directly by killing the host cells they …

Cytokines are soluble proteins that are produced and secreted as part of the immune
response to a variety of tissue insults including infection, cancer, and autoimmunity. Most …

The immediate response to viral infection relies on pattern-recognition receptors (PRRs),
most prominently the Toll-like receptors (TLRs) and the RNA helicases RIG-I and MDA5, as …

Biologists, physicians and immunologists have contributed to the understanding of the
cellular participants and biological pathways involved in inflammation. Here, we provide a …

Does Inflammation Cut to the Heart of the Matter? | Science news careers commentary
Journals Science Science brought to you byGoogle Indexer Log in science science …

INTRODUCTION Even with intimate exposure to a virus, some people fail to become
infected. Variable transmission partly depends on the dose and duration of exposure but is …

The immune system plays a major role in human health and disease, and understanding
genetic causes of interindividual variability of immune responses is vital. Here, we isolate …